Results 21 to 30 of about 114,786 (336)

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou, Hana Kubova, Stéphane Auvin, Massimo Mantegazza, Melissa Barker‐Haliski, Aristea S. Galanopoulou, Christopher A. Reid, Bridgette D. Semple   +7 more
wiley   +1 more source

EXTRACTION AND IDENTIFICATION OF ATROPIN FROM DATURA INNOXIA AND STUDYING EFFECT ON SOME ENZYMES. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2012
The work included extraction and identification of atropine.The alkaloid of atropine was extracted from Datura Innoxia using water extraction method.The purification of atropine was accomplished using several chromatographic Thin Layer chromatography ...
FIRAS T.MAHER, AYAD S. HAMMED, TAPPAN K.KAKAH   +2 more
doaj   +1 more source

Effects of low-concentration atropine eye drops on the optical quality of the eyes in myopic children

Indian Journal of Ophthalmology, 2022
Purpose: The present study was performed to compare the optical quality of the eyes of myopic children before and after treatment with atropine eye drops of different concentrations. Methods: In the study population of 71 patients (131 eyes), 34 patients
Weiran Li, Yiting Cao, Jibo Zhou
doaj   +1 more source

Atropine eye-drop-induced acute delirium: a case report

General Psychiatry, 2020
Atropine is an anticholinergic drug which is used in both parental and topical routes. Topical eye-drops of atropine sulfate are used as mydriatic and cycloplegics.
Dheerendra Kumar Mishra, Vijay Niranjan, Prashant Maravi, Amrendra Singh   +3 more
doaj   +1 more source

The optimal atropine concentration for myopia control in Chinese children: a systematic review and network Meta-analysis [PDF]

International Journal of Ophthalmology
AIM: To figure out whether various atropine dosages may slow the progression of myopia in Chinese kids and teenagers and to determine the optimal atropine concentration for effectively slowing the progression of myopia.
Xiao-Yan Wang, Hong-Wei Deng, Jian Yang, Xue-Mei Zhu, Feng-Ling Xiang, Jing Tu, Ming-Xue Huang, Yun Wang, Jin-Hua Gan, Wei-Hua Yang   +9 more
doaj   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Atropine Differentially Modulates ECM Production by Ocular Fibroblasts, and Its Ocular Surface Toxicity Is Blunted by Colostrum

Biomedicines, 2020
Background: The etiology and the mechanism behind atropine treatment of progressive myopia are still poorly understood. Our study addressed the role of scleral and choroidal fibroblasts in myopia development and atropine function.
Martina Cristaldi, Melania Olivieri, Salvatore Pezzino, Giorgia Spampinato, Gabriella Lupo, Carmelina Daniela Anfuso, Dario Rusciano   +6 more
doaj   +1 more source

State-Dependent and -Independent Effects of Dialyzing Excitatory Neuromodulator Receptor Antagonists into the Ventral Respiratory Column [PDF]

, 2017
Unilateral dialysis of the broad-spectrum muscarinic receptor antagonist atropine (50 mM) into the ventral respiratory column [(VRC) including the pre-Bötzinger complex region] of awake goats increased pulmonary ventilation (V̇i) and breathing frequency (
Burgraff, Nicholas J., Crumley, Emma, Forster, Hubert V., Hodges, Matthew R., Langer, Thomas M., III, Neumueller, Suzanne E., Pan, Lawrence, Talwar, Sawan   +7 more
core   +2 more sources

Growth Differentiation Factor 15 Induces Gastric Fundus Contraction Involving Cholinergic Excitation: Morphofunctional Evidence in Rodent Models [PDF]

J Cell Mol Med
ABSTRACT Growth Differentiation Factor 15 (GDF15) is a peptide from the transforming growth factor (TGF)‐β superfamily, typically found at low levels in mammalian tissues, but significantly upregulated during cellular stress or injury. Initially recognised for its role in inducing anorexia and vomiting, GDF15 is now seen as a broader regulator of ...
Garella R, Palmieri F, Tarchi L, Tani A, Chellini F, Guarnieri G, Morelli A, Bernacchioni C, Rovero P, Ricca V, Castellini G, Sassoli C, Squecco R.   +12 more
europepmc   +2 more sources

The action of atropine and acetylcholine on the pace maker ganglion cells of limulus heart [PDF]

, 1960
On the median nerve trunk-heart muscle preparation of Limulus the authors studied the effects of atropine and acetylcholine upon the pace maker ganglion cells.
Hukuhara, Takesi, Okada, Hiromasa, Yamagami, Matuyosi   +2 more
core   +1 more source