A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, Juan Carlos +5 more
core +4 more sources
High‐concentration atropine induces corneal epithelial cell apoptosis via miR‐30c‐1/SOCS3
Atropine is an anticholinergic drug widely used in the field of ophthalmology, but its abuse can cause cytotoxicity to the cornea, resulting in blurred vision.
Xi‐Jia Chen, Po Hu, Shu Yi
doaj +1 more source
PurposeTo compare the myopic progression in children treated with 0. 01% atropine and those who discontinued atropine during the 2022-home quarantine in Shanghai.MethodsIn this retrospective study, children aged 6–13 years with follow-up visits before ...
Manrong Yu +8 more
doaj +1 more source
Current trends among pediatric ophthalmologists to decrease myopia progression—an international perspective [PDF]
Purpose To explore what the current worldwide preferred practice patterns of pediatric ophthalmologists are to decrease myopia progression among their patients.
Farzavandi, Sonal K. +5 more
core +1 more source
Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion [PDF]
Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected.
Graham, V. +8 more
core +1 more source
Anticholinergic therapy for acute asthma in children. [PDF]
Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in ...
Beakes +49 more
core +2 more sources
Dynamic regulation of quaternary organization of the M1 muscarinic receptor by subtype-selective antagonist drugs [PDF]
Although rhodopsin-like G protein-coupled receptors can exist as both monomers and non-covalently associated dimers/oligomers, the steady-state proportion of each form and whether this is regulated by receptor ligands is unknown.
Godin, Antoine G. +4 more
core +1 more source
Swallowing Disorder and Inhibition of Cough Reflex Induced by Atropine Sulfate in Conscious Dogs
In this study, the effects of atropine sulfate (atropine) on swallowing and cough reflex were evaluated in the two experimental models in conscious dogs.
Tadashi Tsubouchi +5 more
doaj +1 more source
Novel Non-Invasive Treatment for Canine Corneal Ulcers: Application of New Extracellular Matrix-Based Sticky Sealants. [PDF]
ABSTRACT Objective To evaluate the clinical efficacy of a newly developed adhesive tissue sealant, gelatinized cornea‐derived decellularized extracellular matrix (Cod‐ECM) for the treatment of stromal ulcers in dogs. Animal Studied This study included 60 eyes of 56 dogs diagnosed with stromal ulcerative keratitis, limited to corneal ulcers involving ...
Yang SJ +4 more
europepmc +2 more sources
Neuroprotective Effects of Antidotes in Soman-Poisoned Rats
1. The neuroprotective effects of antidotes (atropine, obidoxime/atropine mixture, HI-6/atropine mixture) on rats poisoned with soman at a sublethal dose (48 μg/kg i.m.; 60% of LD50 value) were studied.
Jiří Kassa, Marie Koupilová
doaj +1 more source

