Results 51 to 60 of about 111,342 (315)

Dynamic regulation of quaternary organization of the M1 muscarinic receptor by subtype-selective antagonist drugs [PDF]

open access: yes, 2016
Although rhodopsin-like G protein-coupled receptors can exist as both monomers and non-covalently associated dimers/oligomers, the steady-state proportion of each form and whether this is regulated by receptor ligands is unknown.
Godin, Antoine G.   +4 more
core   +1 more source

Effect of Topical Atropine on Wound Contraction in Swiss Albino Mice : A preliminary report

open access: yesIndian Journal of Plastic Surgery, 2000
The influence of topical application of atropine ointment was studied in artificially wounded Swiss albino mice. Full thickness excision wounds were made surgically on the dorsum of mice.
P Kumar, G C Jagetia
doaj   +1 more source

Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]

open access: yesWorld Journal of Research and Review (WJRR) ISSN:2455-3956, Volume-4, Issue-5, May 2017 Pages 26-30, 2020
Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv  

A Role for the Kolliker-Fuse Nucleus in Cholinergic Modulation of Breathing at Night During Wakefulness and NREM Sleep [PDF]

open access: yes, 2010
For many years, acetylcholine has been known to contribute to the control of breathing and sleep. To probe further the contributions of cholinergic rostral pontine systems in control of breathing, we designed this study to test the hypothesis that ...
Bonis, Joshua M.   +8 more
core   +1 more source

Changes in neuromuscular structure and functions of human colon during ageing are region-dependent [PDF]

open access: yes, 2018
Objective: To determine if human colonic neuromuscular functions decline with increasing age.Design: Looking for non-specific changes in neuromuscular function, a standard burst of electrical field stimulation (EFS) was used to evoke neuronally mediated (
Ahmed, Shafi   +13 more
core   +2 more sources

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao   +15 more
wiley   +1 more source

MALDI imaging mass spectrometry revealed atropine distribution in the ocular tissues and its transit from anterior to posterior regions in the whole-eye of rabbit after topical administration.

open access: yesPLoS ONE, 2019
It is essential to elucidate drug distribution in the ocular tissues and drug transit in the eye for ophthalmic pharmaceutical manufacturers. Atropine is a reversible muscarinic receptor used to treat various diseases. However, its distribution in ocular
Naoto Mori   +6 more
doaj   +1 more source

Effect of intravenous atropine on treadmill stress test results in patients with poor exercise capacity or chronotropic incompetence

open access: yesمجلة كلية الطب, 2010
Background: stress test (EST) is one of the main diagnostic and prognostic tests for ischemic heart disease. However, its usefulness depends on achieving target heart rate, then chronotropic incompetence and poor exercise capacity limits its utility.
Abdul ameer J. Awad
doaj   +1 more source

Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]

open access: yes, 1984
Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
A.B. Steffens   +35 more
core   +4 more sources

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