Results 71 to 80 of about 10,005,921 (298)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Romantic attachment and commitment: a mediation model
, 2017 As defined by Bowlby (1969, 1982), attachment system is directed to maintain closeness to a significant other who is able to give support and protection in dangerous situations.
BRUNETTO, MARTINA +3 more
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How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Wait Up!: Attachment and Sovereign Power [PDF]
, 2014 Sociologists and feminist scholars have, over many decades, characterised attachment as a social construction that functions to support political and gender conservatism.
Monica Greco +7 more
core +2 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Attachment at work: its construct, discriminant, and predictive validity. [PDF]
, 2007 This dissertation is concerned with Attachment Theory (e.g. Bowlby, 1969/82 1973 1980) as it may apply to adults at work, with particular attention to the bearing of attachment orientation on management style and job performance.
Neustadt, E.
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, 2019 Despite increased engagement of men in parenting, paternal caregiving representations have not been investigated, and potential gender differences in the links between parents’ attachment representations and their caregiving representations are ...
Lund University., Psouni, Elia,
core +2 more sources
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
[Advertisement for Lawson's Never-Fail Finder Attachment]
, 1940 Recto: [descriptive text not transcribed]. Verso: [imprinted] Lawson's Never-Fail Finder Attachment Co. McGregor, Texas. [descriptive text not transcribed]
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