Results 111 to 120 of about 193,280 (308)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Recent Advances in Cardiac Troponin I Based Sensors for Detection of Human Heart Attack

open access: yes, 2016
Cardiovascular disease (CVD) is considered as a major life threat in human globally, and with time more sophisticated technique for estimating and therapeutics is still desirable.
Bhatnagar, Deepika   +4 more
core  

Intrusion Detection and Security Assessment in a University Network [PDF]

open access: yes, 2010
This thesis first explores how intrusion detection (ID) techniques can be used to provide an extra security layer for today‟s typically security-unaware Internet user.
Fitzpatrick, Darren
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Impact of bandwidth and channel variation on presentation attack detection for speaker verification

open access: yes, 2017
Vulnerabilities to presentation attacks can undermine confidence in automatic speaker verification (ASV) technology. While efforts to develop countermeasures, known as presentation attack detection (PAD) systems, are now under way, the majority of past ...
Liu,Wei Ming   +7 more
core  

High Performance Network Worm Detection Engine Using Memory Efficient Circular Buffer. [PDF]

open access: yes, 2007
This paper presents the implementation of a memory efficient circular buffer to ensure a high performance network worm detection engine.
Pasha, Muhammad Fermi   +4 more
core  

Attack detection model for BCoT based on contrastive variational autoencoder and metric learning

open access: yesJournal of Cloud Computing: Advances, Systems and Applications
With development of blockchain technology, clouding computing and Internet of Things (IoT), blockchain and cloud of things (BCoT) has become development tendency. But the security has become the most development hinder of BCoT.
Chunwang Wu   +6 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Intrusion detection and management over the world wide web [PDF]

open access: yes, 2010
As the Internet and society become ever more integrated so the number of Internet users continues to grow. Today there are 1.6 billion Internet users. They use its services to work from home, shop for gifts, socialise with friends, research the family ...
Luan, Hai Ying, Hai Ying Luan
core  

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

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