Results 231 to 240 of about 28,264 (289)

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Clinical profile of headache attributed to anxiety and depressive disorders: an observational study. [PDF]

Front Neurol
Chen B, Zhang S, Yang J, Yan X, Wang C, Wan D.   +5 more
europepmc   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Fish alter locomotor and feeding kinematics to capture aerial prey. [PDF]

Proc Biol Sci
Axlid EG, Lowe C, Wang ES, Higham TE.
europepmc   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Cholecystokinin upregulation in mPFC leads to social defeat-induced anxiety susceptibility in neuroligin 3 R451C knockin mice. [PDF]

Mol Autism
Fu Y, Xu Y, Li H, Jiang K, Yang Q, Li Z, Chen J, Ju Y, Xu K, Yan H, Ge J, Li S, Yan K, Dou W, Wang X, Luo J, Li B, Cao W.   +17 more
europepmc   +1 more source

Woody seeds and seedlings are unresponsive to herbivore kairomones. [PDF]

AoB Plants
Headrick KC, Pellegrini BA, Santiago EM, Overstrum KM, Bhavanam SP, Orians CM, Orrock JL, Preisser EL.   +7 more
europepmc   +1 more source

Design of robust networks via reinforcement learning prompts the emergence of multi-backbones. [PDF]

Nat Commun
Zhu B, Zhu T, Gao J, Havlin S, Li D.
europepmc   +1 more source

Strong Target Attack on Hypergraph Neural Networks via Label Poisoning and Structure Modification. [PDF]

Entropy (Basel)
Huang J, Sun Q, Zhang N, Zheng M.
europepmc   +1 more source