Results 181 to 190 of about 28,454 (287)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Enhancing internet of things intrusion detection through high-performance boosting ensemble learning. [PDF]

Sci Rep
Yakovyna V, Fadieiev A.
europepmc   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Distributed denial of service detection and mitigation in software-defined networking-enabled software-defined wide area networks. [PDF]

PLoS One
Musa M, Ang TF, Chen YL, Bhatti UA, Ku CS, Luo Y, Chen J, Por LY.   +7 more
europepmc   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source

Prioritization of patients at risk of heart attack using a novel full-objective ITARA based on Random Forest and Decision tree. [PDF]

Sci Rep
Amini N, Hashemkhani Zolfani S, Cavallaro F.   +2 more
europepmc   +1 more source

Classifying avian drinking behaviour: ecological insights and implications in a changing world

Biological Reviews, EarlyView.
ABSTRACT Water is a fundamental currency of life, and its availability significantly influences animal behaviour, physiology and distributions. However, our knowledge around the dependence on water for drinking and the direct and indirect mechanisms driving related behaviours remains partial in the context of changing climates. Here, we review patterns
Shannon R. Conradie, Marc T. Freeman
wiley   +1 more source

Biological Barriers to Forest Pest Invasions: A Novel Host Tree Slows Mountain Pine Beetle Range Expansion. [PDF]

Ecol Evol
Johnson EC, Musso A, Cullingham C, Lewis MA.   +3 more
europepmc   +1 more source

Ecology and evolution of pyrazines in insects

Biological Reviews, EarlyView.
ABSTRACT Chemical communication is the oldest and most widespread form of signalling among and within organisms. Among the many compounds involved in such communication, pyrazines – nitrogen‐containing heterocyclic molecules – are especially intriguing due to their widespread occurrence across the tree of life, from bacteria and fungi to insects and ...
Zowi Oudendijk, Niklas Wahlberg, Johanna Mappes   +2 more
wiley   +1 more source

Associations between phloem microbiota and metabolomes in three North American ash species (Fraxinus spp.) susceptible to emerald ash borer (Agrilus planipennis). [PDF]

Environ Microbiome
Mogouong Tambue J, Yager C, Bushley KE.
europepmc   +1 more source