Results 51 to 60 of about 5,090,991 (269)

The data on the relationship between polymorphism of HTR1B and DBH genes and attention-deficit hyperactivity disorder in adults with or without substance use disorders

Data in Brief, 2018
There is a positive relationship between attention-deficit hyperactivity disorder and tendency toward drug use in numerous studies. The present study was aimed to investigate the relationship between polymorphism of serotonin receptor 1B gene (HTR1B) and
Mojgan Khademi, Katayoon Razjouian, Rozita Davari-Ashtiani, Fariba Arabgol, Firoozeh Jafari, Hosein Darvish   +5 more
doaj   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source

Attention Deficit Hyperactivity Disorder (ADHD) and Ethnicity: A Literature Review [PDF]

, 2005
Attention Deficit Hyperactivity Disorder (ADHD) is one of the most expensive mental disorders, costing U.S. citizens $77 billion every year (Reinberg, 2004). Although ADHD effects between 3-7% of U.S.
Bryant, Shanel M.
core  

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Functional analysis of ADHD in children using nonlinear features of EEG signals [PDF]

Journal of Integrative Neuroscience, 2018
Attention deficit hyperactivity disorder is a neurodevelopmental condition associated with varying levels of hyperactivity, inattention, and impulsivity.
Shiva Khoshnoud, Mohammad Ali Nazari, Mousa Shamsi
doaj   +1 more source

Trajectories of growth and symptoms of attention-deficit/hyperactivity disorder in children : a longitudinal study [PDF]

, 2011
Background Empirical evidence suggests that prenatal growth is associated with attention deficit/hyperactivity disorder (ADHD) and its symptoms. Data on the importance of postnatal growth is, however scanty.
Dieter Wolke, Aulikki Lano, Kati Heinonen, Andersson Sture, Lano Aulikki, Eriksson Johan G, Andersson, Sture, Kajantie, Eero, Raikkonen, Katri, Johan G Eriksson, Eero Kajantie, Heinonen, Kati, Vartia Timo, Eriksson, Johan G., Räikkönen Katri, Sture Andersson, Timo Vartia, Heinonen Kati, Wolke Dieter, Vartia, Timo, Wolke, Dieter, Lano, Aulikki, Katri Räikkönen, Kajantie Eero, Pesonen Anu-Katriina, Anu-Katriina Pesonen, Pesonen, Anu-Katriina   +26 more
core   +2 more sources

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

How teachers′ knowledge of attention deficit hyperactivity disorder makes difference in doctors′ diagnostic decisions and management?

Saudi Journal of Medicine and Medical Sciences, 2015
Objective: The teacher′s knowledge plays a key role in the process of assessing, screening, and diagnosing attention deficit hyperactivity disorder.
Mohamed S Khalil, Elham Jenahi
doaj   +1 more source

Executive Function Problems and Treatment in Children and Adolescents with Attention Deficit and Hyperactivity Disorder [PDF]

Psikiyatride Güncel Yaklaşımlar, 2019
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that may seriously affect youth’s home, school, and social functioning.
Ugur Savci, Ali Evren Tufan, Yusuf Ozturk, Mehmet Akif Cansiz   +3 more
doaj   +1 more source

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

Advanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen, Bin He, Kuan Liu, Zhuo Ma, Bin Xu   +4 more
wiley   +1 more source