The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
The eye–brain neuroimmune axis triggers immune activation and disrupts pathological neuronal connectivity to extend glioblastoma survival. ABSTRACT As an anatomical extension of the central nervous system (CNS), the eye harbors rich neural and immune interfaces with the brain. However, the integrated immunological and neurological nexus between the eye
Mingyue Cui +9 more
wiley +1 more source
Correction to "Probiotic Supplementation and Executive Function in Children With Attention-Deficit/Hyperactivity Disorder". [PDF]
europepmc +1 more source
Assessment of child-parent dyads' health-related quality of life in learning disorder care: a cross-sectional study in eastern China. [PDF]
Sun L +8 more
europepmc +1 more source
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen +11 more
wiley +1 more source
Erratum: Comparison of the performance of machine learning algorithms for the task-switching functional magnetic resonance imaging data for distinguishing attention deficit hyperactivity disorder from bipolar disorder. [PDF]
europepmc +1 more source
Causal relationship between inflammatory proteins and attention deficit hyperactivity disorder: A serum-metabolites-mediated Mendelian randomization analysis. [PDF]
Zhou K, Zhang Q, Liu M, Yan Y, Wang J.
europepmc +1 more source
Happiness and Attention Deficit/Hyperactivity Disorder Symptoms as Mediated by Subjective Health Conditions: A Nationwide Cross-Sectional Internet Survey. [PDF]
Sugawara N +3 more
europepmc +1 more source
Symptomatic improvement in fibromyalgia after treatment of comorbid attention deficit hyperactivity disorder: a case report. [PDF]
Chiu J, Nikirk J, Brown A, Woolford M.
europepmc +1 more source
Cortical morphometric inverse divergence in attention-deficit/hyperactivity disorder correlates with cell-type-specific, laminar-specific and developmental transcriptomic signatures. [PDF]
Zeng Y, Yang L, Cui Z, Cao Q.
europepmc +1 more source

