Results 131 to 140 of about 4,536,703 (270)

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

Epilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley, Peter Widdess‐Walsh, Christine Linehan, Danielle M. Andrade, Norman Delanty, Patrick B. Moloney   +5 more
wiley   +1 more source

Reversal of refractory epilepsy in an adult with GAMT deficiency: A case report and comparative literature review

Epilepsia Open, EarlyView.
Abstract Objective Guanidinoacetate methyltransferase (GAMT) deficiency is a rare autosomal recessive creatine biosynthesis disorder. Reports specifically focusing on adult patients remain scarce. Methods We report a 52‐year‐old female (the oldest documented case of GAMT deficiency to date) presenting with severe intellectual disability, refractory ...
Wei‐Hung Sung, Hsi Chen, Che‐Wei Hsu, Meng‐Han Tsai   +3 more
wiley   +1 more source

‘We Need Help Too’—The Forgotten Stakeholders: Exploring the Needs of Carers During Their Young Persons' Transition From Child to Adult Eating Disorder Services

European Eating Disorders Review, EarlyView.
ABSTRACT Background Carers are essential in their young person's recovery during transition from child to adult eating disorder services. Despite recommendations, carer's own needs can be overlooked in transition planning. Subsequently, carers experience distress in supporting their young person and navigating the transition.
Isabel Lenham, Maria Livanou, Anya Heneghan, Grace Hill, Alanta McKenzie, Marta Marlais, Francesca Marshall, Zara Smalley, Eleni Xanthopoulou, Nora Kornai, Jessica Wilks, Ailsa McKay, Jun Teh, Julian Baudinet   +13 more
wiley   +1 more source

Prevalence of Medical and Psychiatric Comorbidities in Paediatric ARFID: A Meta‐Analysis

European Eating Disorders Review, EarlyView.
ABSTRACT Background Avoidant/Restrictive Food Intake Disorder (ARFID) is increasingly recognized as a complex paediatric feeding and eating disorder associated with significant medical and psychiatric burden. Methods This systematic review and meta‐analysis followed PRISMA guidelines and was prospectively registered in PROSPERO (CRD420251241490 ...
Nuria Blay Borch, Patricia Sanazario González, Rut Vila del Pozo, Juan David Duque‐Yemail, Laura Gisbert‐Gustemps, Imanol Setién‐Ramos, María Martínez‐Ramírez, Josep Antoni Ramos‐Quiroga, Jorge Lugo‐Marín   +8 more
wiley   +1 more source

From Anorexia Nervosa Onset to Treatment Initiation: Experiences of Parents and Young People

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To explore how young people (YP) with anorexia nervosa (AN) and parents experience the period from illness onset to treatment initiation, focussing on perceived impacts on family life. Method An exploratory qualitative study employing 15 interviews with YP (aged 13–17 years) and 20 interviews with parents analysed using reflexive ...
Signe Holm Pedersen, Stine Bay, Julie Midtgaard, Ulla Moslet, Maria Maack Gregaard, Anne Katrine Pagsberg, Mette Bentz   +6 more
wiley   +1 more source

Evolution from reflex myoclonic epilepsy of infancy to childhood absence epilepsy in NRXN1‐related disorder

Epileptic Disorders, EarlyView.
Shanine Kamgang, Kenneth A. Myers
wiley   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

Ibrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

Maternal overweight and obesity during pregnancy and sex‐dependent dysregulation of the materno‐fetal stress axis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Maternal obesity and excess gestational weight gain (GWG) are linked to adverse perinatal outcomes, potentially via disruption of the maternal–fetal stress axis. Placental HSD11B2 protects the fetus from excess glucocorticoids and may influence fetal programming during maternal metabolic stress.
Thorsten Braun, Marie Hofmann, Rebecca Rancourt, Julia Sommer, Alexandra Kühn, Loreen Ehrlich, Thomas Ziska, Kerstin Melchior, Karen Schellong, Wolfgang Henrich, Sonja Entringer, Katherine Margaret Kennedy, Andreas Plagemann, Deborah Magdalena Sloboda   +13 more
wiley   +1 more source

Lipid‐inclusive metabolomics of infants born after suspected preterm labor according to whether delivery occurred preterm or at term: A prospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize the cord blood metabolic profile of infants born after suspected preterm labor (sPTL) according to whether delivery occurred preterm or at term compared with infants from uncomplicated pregnancies. Study Design Prospective observational cohort study including singleton pregnancies complicated by sPTL and uncomplicated
Lina Youssef, Natalia Abadía‐Cuchí, Juan Lerma‐Irureta, Jesús Orduna, María Savirón, Irene Orera, Ana Medel‐Martinez, Marta Fabre, Jesús González, Pilar Maestro‐Quibus, Sara Ruiz‐Martinez, Jon Schoorlemmer, Diego Lerma, Daniel Oros, Cristina Paules   +14 more
wiley   +1 more source

Benchmarking gut microbiome indices within and across populations

iMetaOmics, EarlyView.
We compared 10 widely used gut microbiome indices in 12,561 American Gut Project participants and 10 external cohorts, testing how well each distinguished people with healthy lifestyles, responded to 79 environmental factors, and associated with 14 chronic conditions. No single index performed best on all three tasks.
Yu Sun, Yuwei Tang, Jieying Ou, Xinghan Wang, Yiwen Yuan, Xi Fu, Yiqun Deng   +6 more
wiley   +1 more source