Results 141 to 150 of about 4,536,703 (270)

Association between attention deficit hyperactivity disorder and keratoconus. [PDF]

Can J Ophthalmol
Mihalache A, Huang RS, Popovic MM, Safir M, Einan-Lifshitz A, Chan CC.   +5 more
europepmc   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

iNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li, Chaoyang Wang, Junci Chong, Zishu Liu, Boying Wang, Shiyu Liu, Xingcai Zhang, Hengrui Liu, Shuanglin Qin, ChuTse Wu, Beidong Chen, Zhigang Chang   +11 more
wiley   +1 more source

GSK3β drives early diabetic tubulopathy via TFEB‐mediated mitochondrial dysfunction

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction, including mitochondrial biogenesis, mitophagy, dynamics and oxidative stress, occurs in the early stages of diabetic tubulopathy, which precede proteinuria and renal histological changes. GSK3β is a potential novel biomarker for the prediction of diabetic tubulopathy.
Lan Yao, Xianhui Liang, Bingyu Li, Bohan Chen, Xiaoyang Wang, Mei Hong, Qi Feng, Yingjin Qiao, Zhangsuo Liu, Kai Wang, Pei Wang   +10 more
wiley   +1 more source

Mentalization and Emotion Regulation Difficulties in Adolescent Girls With Social Anxiety Disorder

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Social anxiety disorder (SAD) is a prevalent disorder that often begins during adolescence, leading to considerable challenges in social functioning and overall mental health. Previous studies have demonstrated that mentalization deficits and emotion regulation difficulties are each independently associated with social anxiety ...
Ayşe Selma Yenen Menderes, Isranur Yenen Sivri, Hande Günal Okumuş, Uğur Ufuk Işın, Makbule Esen Öksüzoğlu, Burcu Ersöz Alan   +5 more
wiley   +1 more source

The Stigmatization of Caregivers of Children With Attention-Deficit/Hyperactivity Disorder: A Systematic Review. [PDF]

Fam Process
Guerin S, McCrossin J, Blanc R, Cappe É.   +3 more
europepmc   +1 more source

Adolescent Withdrawn/Depressed Symptoms: A Pathway From Early Adversity to Later Marijuana Use

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Adverse childhood experiences (ACEs) are robust predictors of marijuana use, yet the developmental mechanisms remain unclear. Building on prior cross‐sectional studies using broad internalizing composites, this study prospectively distinguishes withdrawn/depressed from anxious/depressed symptoms as candidate mediators across ...
Mahsa P. Yousefkhani, Sara A. Vasilenko, Rachel A. Razza   +2 more
wiley   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Designing With Clients, Not for Them: Human‐Centered Design as a Complement to Clinical Mental Health Counseling

Journal of Counseling &Development, EarlyView.
ABSTRACT Clinical mental health concerns often emerge before a client's problem is fully understood or safe to disclose. This best‐practice article presents human‐centered design as a complementary metamodel for clinical reasoning and collaborative treatment planning.
Patrick Akos
wiley   +1 more source

The Impact of Mindfulness as a Session‐Introduction on Symptoms and Alliance in Individual Cognitive‐Behavioral Therapy With Children and Adolescents: A Randomized Controlled Trial

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objectives Mindfulness is increasingly being implemented in child and adolescent therapy. However, little is known about its effectiveness in individual settings within a clinical outpatient context. We investigated the effects of session‐introducing mindfulness interventions (IG‐M) compared to session‐introducing relaxation interventions (CG ...
Julia Kalmar, Ines Baumann, Elena Schleiting, Anne Grünert, Eva Vonderlin, Katajun Lindenberg, Andreas B. Neubauer, Thomas Heidenreich, Johannes Mander   +8 more
wiley   +1 more source