Results 121 to 130 of about 3,121,297 (329)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Scientific ReportsWearable sensors are widely used in medical applications and human–computer interaction because of their portability and powerful privacy. Human activity identification based on sensor data plays a vital role in these fields.
Xiong Wei, Zifan Wang
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
End-to-End Point Cloud Completion Network with Attention Mechanism [PDF]
, 2022 Yaqin Li +4 more
openalex +1 more source
Brain Mechanisms for Directed Attention [PDF]
Journal of the Royal Society of Medicine, 1978 openaire +5 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Handwritten Amharic Word Recognition With Additive Attention Mechanism
IEEE AccessAmharic stands as the second most widely spoken Semitic language globally, trailing only Arabic. As a result, it is a highly resourceful language for hardcopy-document collection, and automatic recognition technology is required.
Ruchika Malhotra, Maru Tesfaye Addis
doaj +1 more source
Multi-modal co-learning with attention mechanism for head and neck tumor segmentation on 18FDG PET-CT [PDF]
Min Jeong Cho +3 more
openalex +1 more source
Multichannel attention mechanisms fusion based on gate recurrent unit memory network for fine-grained image classification [PDF]
, 2018 Rui Yang, Dahai Li
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source