Current efforts towards safe and effective live attenuated vaccines against African swine fever: challenges and prospects. [PDF]
Infect Dis Poverty, 2021 African swine fever (ASF) is a fatal hemorrhagic disease in domestic pigs and wild boar caused by African swine fever virus (ASFV). Since ASF has been introduced into Europe and Asia, the major pig-raising areas, posing a huge threat to the pork industry
Wang T, Luo R, Sun Y, Qiu HJ.
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How Live Attenuated Vaccines Can Inform the Development of Broadly Cross-Protective Influenza Vaccines. [PDF]
J Infect Dis, 2019 Correspondence: K. Subbarao, MBBS, MPH, WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, 792 Elizabeth Street, Melbourne, VIC 3000, Australia (kanta.subbarao@influenzacentre.org ...
Rudraraju R, Mordant F, Subbarao K.
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Live attenuated vaccines in patients receiving immunosuppressive agents. [PDF]
Pediatr Nephrol, 2023 The use of live attenuated vaccines in patients with immunosuppressive agents is contraindicated in package inserts and guidelines in Japan and other countries.
Kamei K.
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Prevention and Control of Porcine Epidemic Diarrhea: The Development of Recombination-Resistant Live Attenuated Vaccines. [PDF]
Viruses, 2022 Porcine epidemic diarrhea (PED), causing up to 100% mortality in neonatal pigs, is a highly contagious enteric disease caused by PED virus (PEDV). The highly virulent genogroup 2 (G2) PEDV emerged in 2010 and has caused huge economic losses to the pork ...
Niu X, Wang Q.
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Should the world collaborate imminently to develop neglected live-attenuated vaccines for COVID-19? [PDF]
J Med Virol, 2022 The rapid spread of the Delta variant suggests that SARS‐CoV‐2 will likely be rampant for months or years and could claim millions of more lives. All the known vaccines cannot well defeat SARS‐CoV‐2 due to their limited efficacy and production efficiency,
Chen JM.
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The Importance of Quality Control of LSDV Live Attenuated Vaccines for Its Safe Application in the Field. [PDF]
Vaccines (Basel), 2021 Vaccination is an effective approach to prevent, control and eradicate diseases, including lumpy skin disease (LSD). One of the measures to address farmer hesitation to vaccinate is guaranteeing the quality of vaccine batches.
Haegeman A +8 more
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Comparative Evaluation of Lumpy Skin Disease Virus-Based Live Attenuated Vaccines. [PDF]
Vaccines (Basel), 2021 Vaccines form the cornerstone of any control, eradication and preventative strategy and this is no different for lumpy skin disease. However, the usefulness of a vaccine is determined by a multiplicity of factors which include stability, efficiency ...
Haegeman A +8 more
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Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses. [PDF]
Viruses, 2021 Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Stanfield BA +3 more
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Altering Compositional Properties of Viral Genomes to Design Live-Attenuated Vaccines. [PDF]
Front Microbiol, 2021 Live-attenuated vaccines have been historically used to successfully prevent numerous diseases caused by a broad variety of RNA viruses due to their ability to elicit strong and perdurable immune-protective responses.
Pereira-Gómez M +4 more
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Viral Live-Attenuated Vaccines (LAVs): Past and Future Directions. [PDF]
Adv Sci (Weinh)Viral infections continue to pose a significant threat to the health of both humans and animals. Currently, live attenuated vaccines (LAVs) remain the most efficacious and widely utilized tool for combating viral infections. Conventional LAVs involve the
Tang YD, Li Y, Cai XH, Yin X.
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