Safety of Live-Attenuated Vaccines in Children Exposed to Biologic Response Modifiers in Utero. [PDF]
Zerbo O +13 more
europepmc +1 more source
Conducting Controlled human infection model studies in India is an ethical obligation [PDF]
Weighing competing obligations and achieving the “greatest balance” of right over wrong guides an individual, an agency or a country in determining what ought to be done in an ethically challenging situation.
Dholakia, S. Y., Dholakia, Saumil
core
Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti [PDF]
Alexander S. Pym +4 more
openalex +1 more source
Assessment of Two Novel Live-Attenuated Vaccine Candidates for Herpes Simplex Virus 2 (HSV-2) in Guinea Pigs [PDF]
Jonathan D. Joyce +5 more
openalex +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Effect of monovalent and bivalent live attenuated vaccines against QX-like IBV infection in young chickens. [PDF]
Yang CY, Peng P, Liu X, Cao Y, Zhang Y.
europepmc +1 more source
Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman +2 more
wiley +1 more source
Could live attenuated vaccines better control COVID-19? [PDF]
Okamura S, Ebina H.
europepmc +1 more source
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama +16 more
wiley +1 more source

