Results 161 to 170 of about 1,504,385 (337)

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein [PDF]

, 1995
Two myxoma virus-rabbit hemorrhagic disease virus (RHDV) recombinant viruses were constructed with the SG33 strain of myxoma virus to protect rabbits against myxomatosis and rabbit viral hemorrhagic disease.
Bertagnoli, Stéphane, Boilletot, Eric, Boucraut-Baralon, Corine, Gelfi, Jacqueline, Laurent, Sylvie, Le Gall, Ghislaine, Milon, Alain, Petit, Frédérique, Rasschaert, Denis, Vautherot, Jean-François   +9 more
core   +2 more sources

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Genome Plasticity of African Swine Fever Virus: Implications for Diagnostics and Live-Attenuated Vaccines. [PDF]

Pathogens, 2022
Faburay B.
europepmc   +1 more source

Effects of in Vivo Cd8+ T Cell Depletion on Virus Replication in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine [PDF]

, 1999
Karin J. Metzner, Xia Jin, Fred V. Lee, Agegnehu Gettie, Daniel Bauer, Michele Di Mascio, Alan S. Perelson, Preston A. Marx, David D. Ho, Leondios G. Kostrikis, Ruth I. Connor   +10 more
openalex   +1 more source

Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters [PDF]

, 2022
Xueqiao Liu, Hong-Su Park, Yumiko Matsuoka, Celia Santos, Lijuan Yang, Cindy Luongo, Ian N. Moore, Reed F. Johnson, Nicole L. Garza, Peng Zhang, Paolo Lusso, Sonja M. Best, Ursula J. Buchholz, Cyril Le Nouën   +13 more
openalex   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Evaluation of the Safety, Immunogenicity and Virus Shedding of an Intranasal Live Attenuated Bovine Parainfluenza Virus Type 3 Vaccine in Infants [PDF]

, 1999
David P. Greenberg, Sylvia Yeh, Ram Yogev, Keith S. Reisinger, Joel I. Ward, Mark M. Blatter, Sandra J. Holmes, Paul M. Mendelman, Kathleen Coelingh, Iksung Cho   +9 more
openalex   +1 more source

Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties

Biotechnology Progress, EarlyView.
Abstract Nanoemulsions, with droplet sizes between 20 and 200 nm, have emerged as a promising vaccine adjuvant and drug delivery system, enhancing the solubility of hydrophobic drugs for diverse applications. Sterile filtration of nanoemulsions is particularly challenging due to the similar size between the nanodroplets and the 0.2 μm nominal pore size
Shreya Kapila, Randal J. Soukup, Marissa E. Bradley, David Boyd, Andrew L. Zydney   +4 more
wiley   +1 more source

The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation [PDF]

Belén Borrego, Celia Alonso, Sandra Moreno, Nuria de la Losa, Pedro J. Sánchez‐Cordón, Alejandro Brun   +5 more
openalex   +1 more source