A rationally designed oral vaccine induces Immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants [PDF]
, 2019 Médéric Diard +28 more
openalex +1 more source
People and Nature, EarlyView.Abstract Attempts to address biodiversity loss have led to ecosystem and species restoration efforts. Tree species restoration is particularly relevant because of increasing threats from pests and pathogens. However, there are different notions of ‘loss’, as well as sociocultural considerations, including social acceptability, which are often neglected
Fritha West +4 more
wiley +1 more source
Advanced Live Attenuated Vaccines for the Prevention of Respiratory Syncytial Virus Infections in Young Children. [PDF]
J Infect Dis, 2020 Ramilo O +3 more
europepmc +1 more source
Making Common Sense of Vaccines: An Example of Discussing the Recombinant Attenuated Salmonella Vaccine with the Public [PDF]
, 2014 Dorothy J. Dankel +9 more
openalex +1 more source
Live attenuated vaccines: Historical successes and current challenges.
Virology, 2015 P. Minor
semanticscholar +1 more source
The Cinderella tree, Quillaja saponaria – A soap story
PLANTS, PEOPLE, PLANET, EarlyView.Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley +1 more source
Reverse genetic systems: Rational design of coronavirus live attenuated vaccines with immune sequelae. [PDF]
Adv Virus Res, 2020 Ma Z, Li Z, Dong L, Yang T, Xiao S.
europepmc +1 more source
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Rationally Attenuated Vaccines for Venezuelan Equine Encephalitis Protect Against Epidemic Strains with a Single Dose. [PDF]
Vaccines (Basel), 2020 Rossi SL +6 more
europepmc +1 more source