Results 141 to 150 of about 1,152,479 (285)

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Knowledge, Attitudes, and Practices Regarding Oral Cancer Among Patients with Oral Cancer in Hunan Province, China: A Cross-Sectional Study. [PDF]

Patient Prefer Adherence
Lu Y, Peng Q, Su T, Peng C, Li J, Wu Y, Xiong J.   +6 more
europepmc   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Sustainability of assistive technology use for students with severe and multiple disabilities: a mixed methods study of teachers' attitudes and experiences. [PDF]

Front Psychol
Torun Yeterge H.
europepmc   +1 more source

Educating health professionals about disability: ‘attitudes, attitudes, attitudes’ [PDF]

Journal of the Royal Society of Medicine, 2000
M, Byron, P, Dieppe
openaire   +2 more sources

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

Awareness, Knowledge, and Attitudes of Dentists in Türkiye Regarding the 2034 Phase-Out of Dental Amalgam Under the Minamata Convention: A Cross-Sectional Study. [PDF]

Oral Health Prev Dent
Yıldırım AA, Ayyıldız S.
europepmc   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Knowledge, Attitudes, and Perceptions Regarding Mind Mapping Among Undergraduate Respiratory Therapy Students in Saudi Arabia: A Cross-Sectional Study. [PDF]

Adv Med Educ Pract
Turkestani FA, Hakeem J, Alharthi NA, Alharthi R, Al Nufaiei ZF, Al Zhranei RM, Altabee RM, Alodaini S, Bugis A, Alselemi S, Alobaidi NY, Alahmari AD, Zipp GP.   +12 more
europepmc   +1 more source

Attitudes about Attitudes

Michigan Law Review, 2003
Michael J. Gerhardt, Jeffrey A. Segal, Harold J. Spaeth   +2 more
openaire   +2 more sources