Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Nursing Students' Behavioral Intentions Toward Medication Safety: A Cross-Sectional Study Based on the Theory of Planned Behavior. [PDF]
Zarandona J +3 more
europepmc +1 more source
Did "king dirt" and "bumbledom" defeat the objects of the public health act, 1848?: a case study of the political, social and cultural attitudes to publichealth reform in Newcastle-upon-Tyne, Gateshead and Sunderland,1835-1858 [PDF]
Caroline A. Friswell
openalex
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang +5 more
wiley +1 more source
Breastfeeding knowledge and body image affect breastfeeding attitude of pregnant women: a cross-sectional study. [PDF]
Lin D +5 more
europepmc +1 more source
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu +17 more
wiley +1 more source
Evaluating the use and adaptation of implicit attitude measures in older adults: a scoping review protocol. [PDF]
Vinnikova A, Yang Q.
europepmc +1 more source
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang +19 more
wiley +1 more source
Knowledge, attitude and willingness towards hospice care among older adult patients and their family members in the geriatric department in Hubei Province, China: a multi-centre cross-sectional study. [PDF]
Du P, Zhu J, Yang Y, Zhou X, Jiang H.
europepmc +1 more source

