Results 91 to 100 of about 931,693 (302)
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian +7 more
wiley +1 more source
Reasons for Conspiracy of Silence in Caregivers of Patients in Palliative Care
NURE Investigación, 2012 Introduction: The communication at the end-of-life among terminally ill patients, their family and health workers is difficult. The conspiracy of silence is a frequent situation for patients in palliative care and their families, even for health workers ...
Ángela Cejudo López +5 more
doaj
, 1980 Material appearing below is thought to be of particular interest to Linacre Quarterly readers because of its moral, religious, or philosophic content. The medical literature constitutes the primary but not the sole source of such material.
Catholic Physicians\u27 Guild
core +2 more sources
The Author[’s] Remains: Foucault and the Demise of the “Author-Function” [PDF]
, 2002 At several points throughout his career, Foucault suggests that publishing texts without authors’ names attached would be a useful step towards dismantling what he calls the “author-function:” a social and political role structured according to the way ...
Hendricks, Christina
core +1 more source
Advanced Science, EarlyView.Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source
Ban Glyphosate—Does It Affect the Swedish Farmers' Willingness to Grow Cover Crops?
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT The cultivation of cover crops is one of the new Eco‐scheme practices introduced in Sweden. This study examines how the design of policy attributes of these schemes influences farmers' willingness to grow cover crops on arable land, with particular focus on the potential impact of a glyphosate ban.
Vivian Wei Huang +2 more
wiley +1 more source
African Journal of Primary Health Care & Family MedicineBackground: The COVID-19 Pandemic had profound effects on healthcare systems around the world. In South Africa, field hospitals, such as the Mitchell’s Plain Field Hospital, managed many COVID patients and deaths, largely without family presence ...
Charmaine Cunningham +4 more
doaj +1 more source
American Journal of Community Psychology, EarlyView.Abstract Substance use, specifically opioid and methamphetamine use, is of increasing concern among American Indian (AI) populations in the Great Plains. This community‐driven participatory study investigated the impacts of substance use and community‐defined needs in treating addiction.
Brynn Luger +8 more
wiley +1 more source
05. Aesthetics, Humor, and Virtue: Reflections on Richards and the Good Life [PDF]
, 2020 In A Philosopher Looks at the Sense of Humor, Richard C. Richards discusses how one\u27s appreciation of and ability to create incongruities is a necessary condition for developing a sense of humor.
Victor, Elizabeth
core +1 more source