Results 231 to 240 of about 96,813 (310)

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

open access: yesInternational Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim   +22 more
wiley   +1 more source

The rising tide: Trends in induction of labor at term over a 5‐year period at a single centre

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 383-390, April 2025.
Abstract Objective Induction of labor (IOL) is a controversial topic in contemporary obstetric practice, with some suggesting that the increase in elective induction (eIOL) as a potential contributor to increasing cesarean delivery (CD) rates. The objectives of this single‐center study were to examine the rates of IOL, trends in indications for IOL ...
Sarah M. Nicholson   +7 more
wiley   +1 more source

Evaluating the effect of two different training interventions on improving vaginal twin birth rates and provider confidence and knowledge levels: A pre‐ and post‐intervention study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Despite the increasing trend in cesarean section rates in multiple pregnancies, vaginal delivery in twin pregnancies appears both possible and safe. Methods This retrospective multicenter study compared outcomes before and after the implementation of a vaginal twin intervention in two Italian hospitals. In January 2021 in Pescara and
Claudio Celentano   +9 more
wiley   +1 more source

A cross‐sectional study of caesarean deliveries performed by medical doctors and associate clinicians in nine district and regional hospitals in Sierra Leone using the Robson Ten Group Classification System

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Maternal and neonatal mortality remain high in Sierra Leone despite significant decline in the last decade. The aim of the present study was to evaluate obstetric care delivery using the Robson Ten Group Classification System (TGCS), focusing on caesarean delivery (CD) and task‐sharing.
Josien Westendorp   +10 more
wiley   +1 more source

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