Results 161 to 170 of about 49,586 (211)

The phenotypic landscape of p.Ala117Ser transthyretin amyloidosis: distinct clinical profiles and outcomes versus wild-type ATTR. [PDF]

BMC Cardiovasc Disord
Tuntiwongkosee P, Kochaiyapatana P, Phowthongkum P, Amornvit J, Saicharoen K, Chattranukulchai P, Chettakulanurak K, Puwanant S.   +7 more
europepmc   +1 more source

A Comprehensive Review of the Management of Light-Chain (AL) and Transthyretin (ATTR) Cardiac Amyloidosis. [PDF]

Rev Cardiovasc Med
Alkhatib A, Alashqar R, Abdallah AW, Abu-Nejim H, Hammad A, Khraisat O, Abuzaid AS.   +6 more
europepmc   +1 more source

Spinal Stenosis and Carpal Tunnel Syndrome as Surrogates of Transthyretin Amyloid Cardiomyopathy. [PDF]

JACC Adv
De Michieli L, Geyer S, McPhail E, Bydon M, Elder BD, Rosenthal JL, Jurisson M, Kakar S, Cipriani A, AbouEzzeddine O, Dasari S, Kumar S, Gertz M, Grogan M, Dispenzieri A.   +14 more
europepmc   +1 more source

Wild Type Transthyretin Amyloid Cardiomyopathy Hidden Under Ablation-Refractory Atrial Arrhythmias and the Potential Contribution of Tafamidis in Rhythm Control. [PDF]

J Arrhythm
Horie T, Nagata Y, Nozato T, Miyazaki S, Ashikaga T.   +4 more
europepmc   +1 more source

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Stabilizing Transthyretin to Treat ATTR Cardiomyopathy

New England Journal of Medicine, 2018
Transthyretin amyloid cardiomyopathy is caused by intramyocardial deposition of transthyretin-derived amyloid fibrils, which leads to progressive ventricular wall thickening and stiffness of the heart. Once diagnosed, it is associated with a life expectancy of only 2 to 6 years.
C Cristina, Quarta, Scott D, Solomon
exaly   +3 more sources

[The ATTR-ACT trial].

Giornale italiano di cardiologia (2006), 2019
La transtiretina (TTR) è una proteina di trasporto con struttura tetramerica sintetizzata principalmente (99% circa) dal fegato, che a livello ematico trasporta la tiroxina e la proteina legante il retinolo1. Proprio dalla sua funzione deriva il nome “transtiretina” [transthyretin: TRANS(ports)THY(roxin) and RETIN(ol)]. Esistono due tipi di amiloidosi
Rapezzi, C, Gagliardi, C, Milandri, A
openaire   +3 more sources

Inotersen treatment for ATTR amyloidosis

Amyloid, 2019
Until recently there has been limited specific therapy for transthyretin amyloidosis (ATTR). One possible therapy is to reduce the availability of the protein precursor necessary for amyloid fibril...
openaire   +2 more sources

Myelopathy in hereditary ATTR Val30Met amyloidosis patients

Amyloid, 2021
Hereditary transthyretin (ATTRv) amyloidosis is caused by deposition of misfolded transthyretin protein, which aggregates in amyloid fibrils and disrupts several organs [1].
Gonçalo Videira, Diogo Pereira, Hugo Mota Dória, Ana Paula Sousa, Teresa Coelho, Ana Martins da Silva   +5 more
openaire   +2 more sources