Results 1 to 10 of about 51,205 (281)

Transthyretin is a novel innate immune effector against Gram negative bacteria. [PDF]

PLoS Pathogens
Pseudomonas aeruginosa is an opportunistic pathogen that frequently causes severe bloodstream and respiratory infections, yet the interactions between this bacterium and the innate immune system remain poorly investigated.
Tania Bernabé, María Verd, Guillem Ramis, Alex González-Alsina, Mohammad Qadi, Margalida Mateu-Borrás, Antonio Doménech-Sánchez, Sebastián Albertí   +7 more
doaj   +2 more sources

Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease. [PDF]

PLoS ONE, 2015
Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system.
Gonçalo da Costa, Cristina Ribeiro-Silva, Raquel Ribeiro, Samuel Gilberto, Ricardo A Gomes, António Ferreira, Élia Mateus, Eduardo Barroso, Ana V Coelho, Ana Ponces Freire, Carlos Cordeiro   +10 more
doaj   +3 more sources

Serum transthyretin combined with first trimester uterine artery doppler ultrasound for preeclampsia prediction in singleton pregnancies: a prospective observational study [PDF]

Scientific Reports
This study aimed to evaluate the predictive value of serum transthyretin levels in conjunction with uterine artery Doppler ultrasound during the first trimester for predicting preeclampsia.
Siraphat Fungtammasan, Vorapong Phupong
doaj   +2 more sources

Technetium-99m-labeled pyrophosphate uptake in the rectum of a patient with wild-type transthyretin cardiac amyloidosis [PDF]

Radiology Case Reports
Wild-type transthyretin amyloidosis is a disease characterized by deposition of transthyretin amyloid protein in systemic organs and tissues, especially the heart, lungs, tenosynovium, and ligaments.
Koji Takahashi, MD, PhD, Daisuke Sasaki, MRT, Shuhei Yamamoto, MD, Nobuhisa Yamamura, MLT, Yushi Utsunomiya, MD, Hiroe Morioka, MD, Shigeki Uemura, MD, Tomoki Sakaue, MD, PhD, Katsuji Inoue, MD, PhD   +8 more
doaj   +2 more sources

Early Progression of Aortic Stenosis Associated With Iatrogenic Variant Transthyretin Amyloidosis After Domino Liver Transplantation

JACC: Case Reports, 2020
We report a 65-year-old man who underwent aortic valve replacement because of severe aortic stenosis associated with de novo iatrogenic variant transthyretin amyloidosis derived from a liver graft extracted from a patient with hereditary transthyretin ...
Yasuhito Hosoda, MD, Mitsuharu Ueda, MD, PhD, Jun Takaki, MD, Ken Okamoto, MD, PhD, Taro Yamashita, MD, PhD, Toshihiro Fukui, MD, PhD   +5 more
doaj   +2 more sources

Utility of Genetic Testing in Patients with Transthyretin Amyloid Cardiomyopathy: A Brief Review

Biomedicines, 2023
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly diagnosed condition. Although wild-type transthyretin amyloidosis (ATTRwt) is the most common ATTR-CM, hereditary transthyretin amyloidosis (ATTRv) may also occur.
Ana-Maria Merino-Merino, Jorge Labrador-Gomez, Ester Sanchez-Corral, Pedro-David Delgado-Lopez, Jose-Angel Perez-Rivera   +4 more
doaj   +1 more source

Left Ventricular Structure and Function in Transthyretin-Related Versus Light-Chain Cardiac Amyloidosis

Circulation, 2014
Candida Cristina Quarta, Christian Gagliardi, Claudio Rapezzi   +2 more
exaly   +3 more sources

Transthyretin, Immature Platelet Fraction, and Mean Platelet Volume in Normotensive and Preeclampsia Pregnancy

Indonesian Biomedical Journal, 2022
BACKGROUND: Transthyretin protein experiences misfolding and aggregation in preeclampsia due to placental ischemia and inflammation. Placental endothelial damage occurring in preeclampsia stimulates the production of larger young platelets in the bone ...
Asri Ragil Kemuning, Herniah Asti Wulanjani, I Edward Kurnia Setiawan Limijadi, Indranila Kustarini Samsuria, Banundari Rachmawati   +4 more
doaj   +1 more source

Amyloidogenicity assessment of transthyretin gene variants

Annals of Clinical and Translational Neurology, 2022
Objective Hereditary transthyretin‐mediated amyloidosis is a treatable condition caused by amyloidogenic variants in the transthyretin‐gene resulting in severe peripheral neuropathy or cardiomyopathy.
Nicolai B. Grether, Felix Napravnik, Thomas Imhof, Reinhold P. Linke, Jan H. Bräsen, Jessica Schmitz, Maike Dohrn, Christian Schneider, Martin K. R. Svačina, Jörg Stetefeld, Manuel Koch, Helmar C. Lehmann   +11 more
doaj   +1 more source

Health-related quality of life in hereditary transthyretin amyloidosis polyneuropathy: a prospective, observational study [PDF]

, 2020
Background Hereditary Transthyretin Amyloidosis Polyneuropathy is a rare life-threatening neurologic disease that imposes considerable mortality and it is associated with progressive related disabilities.
Coelho, Teresa, Conceição, Isabel, Costa, João, de Carvalho, Mamede, Ferreira, Lara, Inês, Mónica   +5 more
core   +2 more sources