Results 1 to 10 of about 405,002 (265)
White Matter and Neuroprotection in Alzheimer’s Dementia
Molecules, 2020 Myelin is the main component of the white matter of the central nervous system (CNS), allowing the proper electrical function of the neurons by ensheathing and insulating the axons.
Luca Lorenzini +6 more
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ESC Heart FailureObjectives Currently, there are two prognosis staging systems validated for transthyretin amyloidosis (ATTR). We sought to develop a new staging system dedicated to hereditary transthyretin amyloidosis (ATTRv) patients on specific treatments. Methods and
Gabriela Neculae +7 more
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Drug-Induced Amyloid-Related Imaging Abnormalities: A Neurovascular Perspective on Risk Assessment
PharmaceuticalsBackground: Anti-amyloid therapies (AAT) are reshaping the therapeutic landscape of Alzheimer’s disease (AD), yet their implementation remains constrained by the risk of amyloid-related imaging abnormalities (ARIA).
Marialuisa Zedde +8 more
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Medical Humanities, 2017 I watch your eyes tracing my face. Furrowed brows suggest blurred image. Slow, slow, not in haste— Mine is a forgotten visage, Erased …
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Plasmacytoma of the Sternum with Amyloid Deposition – A Cytological Diagnosis
Archives of Medicine and Health SciencesPlasmacytoma with amyloid deposition to be diagnosed on cytology is rare. In the absence of typical clinical presentation and radiological findings, the diagnosis of plasmacytoma may not be suspected.
Durre Aden +3 more
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Pharmaceuticals‘Blood stasis’ (syndrome) (BSS) is a fundamental concept in Traditional Chinese Medicine (TCM), where it is known as Xue Yu (血瘀). Similar concepts exist in Traditional Korean Medicine (‘Eohyul’) and in Japanese Kampo medicine (Oketsu).
Douglas B. Kell +2 more
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MembranesThe transition of peptides or proteins along a misfolding continuum from soluble functional states to pathological aggregates, to ultimately deposit as amyloid fibrils, is a process that underlies an expanding group of human diseases—collectively known ...
Raina Marie Seychell +2 more
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Sex Differences in Autophagy Contribute to Female Vulnerability in Alzheimer's Disease
Frontiers in Neuroscience, 2018 Alzheimer's disease (AD) is the most common form of dementia, with over 5. 4 million cases in the US alone (Alzheimer's Association, 2016). Clinically, AD is defined by the presence of plaques composed of Aβ and neurofibrillary pathology composed of the ...
Erin E. Congdon
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Amyloid and inflammation [PDF]
Proceedings of the National Academy of Sciences, 2013 Thirty human and 10 animal proteins form amyloid fibrils associated with codeposition of P-component (SAP), heparatan sulfate proteoglycans (HSPGs), certain apolipoproteins (e.g., ApoE), as well as other less well-defined “ground substances” that may mitigate fibrillogenesis and tissue-specific deposition in association with aging or disease.
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BiomoleculesCortical uptake in brain amyloid positron emission tomography (PET) is increasingly used for the biological diagnosis of Alzheimer’s disease (AD); however, the clinical and biological relevance of the striatum beyond the cortex in amyloid PET scans ...
Zhengshi Yang +3 more
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