Results 31 to 40 of about 560,049 (292)
Amyloid and tau in the brain in sporadic Alzheimer’s disease: defining the chicken and the egg [PDF]
, 2014 In the October 2013 issue of Acta Neuropathologica there were three very interesting articles on: Amyloid or tau: the chicken or the egg? In the first article, David Mann and John Hardy argued that the deposition of aggregated amyloid β (Aβ) protein in ...
Cheryl A. Hawkes +5 more
core +1 more source
Current Opinion in Neurology, 2012 As amyloid neuropathies have benefited from recent major progress, this review is timely and relevant.The main recent articles on amyloid neuropathy cover its description, methods for diagnosis and therapies. Varied clinical presentations are described in transthyretin (TTR)-familial amyloidosis with polyneuropathy (FAP) and light chain amyloid ...
David, Adams +2 more
openaire +4 more sources
Viruses, 2022 The formation of amyloid fibers is associated with a diverse range of disease and phenotypic states. These amyloid fibers often assemble into multi-protofibril, high-order architectures in vivo and in vitro.
Wesley R. Naeimi, Tricia R. Serio
doaj +1 more source
Inflammatory components in human Alzheimer's disease and after active amyloid-β42 immunization
, 2013 Inflammatory processes are important in the pathogenesis of Alzheimer's disease and in response to amyloid-β immunotherapy. We investigated the expression of multiple inflammatory markers in the brains of 28 non-immunized patients with Alzheimer's ...
Cheaveau, M. +18 more
core +1 more source
Cerebral amyloid angiopathy : new insights from transgenic mice [PDF]
, 2004 Cerebral amyloid angiopathy (CAA) is characterized by the deposition of congophilic material within the walls of small to medium-sized blood vessels of the brain and leptomeninges.
Herzig, Martin C.
core +1 more source
Heterohybridomas producing human immunoglobulin light chains using CD138-selected bone marrow cells
Biochemistry and Biophysics ReportsBackground: Light chain research is hampered by lack of mammalian cell lines producing human light chains (FLC). Therefore, we used heterohybridoma (HH) technology to produce clones making FLC thereby providing tools to study light chain behavior ...
P. Zhou +8 more
doaj +1 more source
AL Amyloidosis for the Cardiologist and Oncologist
JACC. CardioOncology, 2019 AL amyloidosis results from clonal production of immunoglobulin light chains, most commonly arising from a clonal plasma cell disorder. Once considered a nearly uniformly fatal disease, prognosis has improved markedly over the past 15 years ...
Ronald M. Witteles, MD +1 more
doaj +1 more source
, 2012 Many bacteria can assemble functional amyloid fibers on their cell surface. The majority of bacterial amyloids contribute to biofilm or other community behaviors where cells interact with a surface or with another cell. Bacterial amyloids, like all functional amyloids, share structural and biochemical properties with disease-associated eukaryotic ...
Yizhou, Zhou +3 more
openaire +2 more sources
The Development of an Early Diagnostic Method for Alzheimer’s Disease
ProceedingsAlzheimer’s disease (AD) is the most common form of dementia, characterized by neuronal degeneration and death [...]
Yulia K. Styufliaeva +3 more
doaj +1 more source
Transthyretin in high density lipoproteins: association with apolipoprotein A-I
Journal of Lipid Research, 2000 Previous studies have revealed the presence of transthyretin (TTR) on lipoproteins. To further address this issue, we fractionated plasma lipoproteins from 9 normal individuals, 10 familial amyloidotic polyneuropathy (FAP) patients, and 19 hyperlipidemic
Mónica Mendes Sousa +2 more
doaj +1 more source