Results 191 to 200 of about 8,194 (217)

Tafamidis: a selective transthyretin stabilizer to treat wild-type ATTR amyloidosis and hereditary ATTR amyloidosis with cardiomyopathy

Drugs of Today, 2019
Plasma protein transthyretin (TTR) can undergo conformational change resulting in the formation of amyloid fibrils that can then cause amyloidosis. This can occur spontaneously in individuals over the age of 70-80 resulting in wild-type transthyretin amyloidosis (ATTR) (with cardiomyopathy). This then progresses to fatal cardiac failure.
openaire   +2 more sources

[Carpal tunnel syndrome and ATTR-amyloidosis].

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2019
Carpal tunnel syndrome is the most common compression syndrome of a peripheral nerve. It mostly affects patients older than 50 years. One cause for a carpal tunnel syndrome is transthyretin (ATTR) amyloid, which deposits in the carpal tunnel tissue. Carpal tunnel syndrome can be the first symptom of ATTR amyloidosis, which in the worst case leads to ...
Katharina, Hahn, Peter, Urban, Rolf Rüdiger, Meliß, Hans-Detlef, Axmann, Frank, Siebert, Christoph, Röcken   +5 more
openaire   +1 more source

Cardiac amyloidosis - ATTR

2022
openaire   +1 more source

ATTR Amyloidosis: Current and Emerging Management Strategies

JACC: CardioOncology, 2021
Jan M Griffin, Justin L Grodin, Mathew S Maurer   +2 more
exaly  

Transthyretin cardiac amyloidosis (ATTR) cardiac amyloidosis

2022
openaire   +1 more source

Efficacy of Tafamidis in Patients With Hereditary and Wild-Type Transthyretin Amyloid Cardiomyopathy

JACC: Heart Failure, 2021
Claudio Rapezzi, Thibaud Damy, Jose Nativi-Nicolau   +2 more
exaly  

Detection of ATTR aggregates in plasma of polyneuropathic ATTR-V30M amyloidosis patients

AbstractATTR amyloidosis is caused by the deposition of transthyretin amyloid fibrils in tissues often leading to organ failure and death. The clinical spectrum of this disease is highly diverse and dependent on many factors including the presence or absence of mutations within the transthyretin protein and/or an individual’s ancestry.
Rose Pedretti, Lanie Wang, Justin L. Grodin, Ahmad Masri, Jeffery Kelly, Lorena Saelices   +5 more
openaire   +1 more source

Screening for ATTR amyloidosis in the clinic: overlapping disorders, misdiagnosis, and multiorgan awareness

Heart Failure Reviews, 2021
Chafic Karam, Mathew S Maurer
exaly  

Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy

Journal of Neurology, 2020
David Adams, João Melo Beirão, Morie A Gertz   +2 more
exaly  

ATTR Epidemiology, Genetics, and Prognostic Factors

Methodist DeBakey Cardiovascular Journal, 2022
Chukwuemeka A Obi, William Mostertz, Jan M Griffin   +2 more
exaly