Results 91 to 100 of about 720,931 (344)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Global attractivity of a discrete cooperative system incorporating harvesting

open access: yes, 2016
A discrete cooperative model incorporating harvesting that takes the form x(k+1)=x(k)exp{r1−Eq−b1x(k)−a1x(k)y(k)+k1},y(k+1)=y(k)exp{r2−b2y(k)−a2y(k)x(k)+k2} $$\begin{aligned}& x(k+1) = x(k)\exp \biggl\{ r_{1}-Eq-b_{1}x(k)- \frac {a_{1}x(k)}{y(k)+k_{1 ...
Fengde Chen, Huiling Wu, Xiangdong Xie
semanticscholar   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

L’extension de la ville de Tizi-Ouzou vers ses flancs est et ouest : quelle alternative à la contrainte foncière ?

open access: yesإنسانيات, 2011
Like a torrent looking for its route, Tizi-Ouzou engulfs in the slightest breach, in the slightest gully to both achieve and check its extension. Several factors such as the rarity of land for building, the nature of the soils, the data concerning state ...
Mohamed Laiche, Mouloud Sadoudi
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Global attractivity in monotone and subhomogeneous almost periodic systems [PDF]

open access: yes, 2003
A global attractivity theorem is first proved for a class of skew-product semiflows. Then this result is applied to monotone and subhomogeneous almost periodic reaction–diffusion equations, ordinary differential systems and delay differential equations ...
Zhao, Xiao-Qiang
core   +1 more source

CHEMOCOMMUNICATION AT HUMANS AND THE POSSIBILITY OF NON-INVASIVE ASSESSMENT OF THEIR FUNCTIONAL AND PSYCHOSOCIAL STATE ON THE BASIS OF VOLATILE METABOLISM PRODUCTS

open access: yesВестник Кемеровского государственного университета, 2013
Subjective estimation of intensity and attractivity of the odor of sweat collected in axillary pits on filter paper is investigatedat 155 young males and 128 young females who were both donors and recipients of odor samples.
N. A. Litvinova   +7 more
doaj  

Physical Attractiveness

open access: yes, 2016
One of the most fundamental problems facing an individual is mate selection: how do we choose a partner? It is important that we are sensitive to the physical cues that honestly signal that one individual is more desirable (i.e. fitter and with a better reproductive potential) than another, and use them to choose the partner which is most likely to ...
Martin Tovee, P. L. Cornelissen
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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