Results 61 to 70 of about 669,840 (357)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Stability analysis for a rational difference equation
Arab Journal of Basic and Applied Sciences, 2020 Most qualitative behaviours of difference equations are rapidly investigated nowadays. This can be attributed to the fact that it is often sophisticated to construct the exact solutions of most difference equations. This article is written to analyse the
M. B. Almatrafi, Marwa M. Alzubaidi
doaj +1 more source
Dynamics in an n-Species Lotka–Volterra Cooperative System with Delays
Axioms, 2023 We studied a class of generalized n-species non-autonomous cooperative Lotka–Volterra (L-V) systems with time delays. We obtained new criteria on the dynamic properties of the systems. First, we obtained the boundedness and permanence of the system using
Zhao Jiang +2 more
doaj +1 more source
, 2015 In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove the existence of a unique positive almost periodic ...
Anh, Trinh Tuan +2 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Restricted total stability and total attractivity
Electronic Journal of Differential Equations, 2006 In this paper the new concepts of restricted total stability and total attractivity is formulated. For this purpose the classical theory of Malkin with suitable changes and the theory of limiting equations, introduced by Sell developed by ...
Giuseppe Zappala'
doaj
Yorke and Wright 3/2-stability theorems from a unified point of view [PDF]
, 2003 We consider a family of scalar delay differential equations $x'(t)=f(t,x_t)$, with a nonlinearity $f$ satisfying a negative feedback condition combined with a boundedness condition.
Aplicada Ii +4 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
L’activité informatique et l’accessibilité économique
Netcom, 2009 Through the study of three territories of the Parisian metropolis, in relation to a political, economic and territorial approach, our analysis results in drawing a picture on the tendencies of localization of the computing activity which take place in ...
Maxime Schirrer
doaj +1 more source
Some Rural Attractions which Attract Tourists
Asian Journal of Agriculture and Rural Development, 2019 Developing rural tourism is a comprehensive strategy for improving the rural economy. The Structure Equation Model (SEM) approach was applied to test how attraction and experiential values of a rural region affect the tourists’ satisfaction and their decision to revisit. After interviewing 353 tourists during their trip to Hakka County, Miaoli, Taiwan,
Shu-Yi Chi +2 more
openaire +2 more sources