Results 61 to 70 of about 15,461 (245)
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Chaotic characteristics and attractor evolution of friction noise during friction process
Friction, 2017 Friction experiments are conducted on a ring-on-disk tribometer, and friction noise produced during the friction process is extracted by a microphone.
Cong Ding +4 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Attractor – a new turning point in drug discovery
Drug Design, Development and Therapy, 2019 Xucan Hou, Meng Li, Congmin Jia, Xianbao Zhang, Yun WangDepartment of Traditional Chinese Medicine Information Fusion and Utilization, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Yun WangDepartment of ...
Hou X, Li M, Jia C, Zhang X, Wang Y
doaj
IEEE Access, 2019 This paper proposes a multi-attractor period multi-scroll chaotic system and a second-generation current-controlled current conveyor (CCCII) with a wide tunable range of intrinsic resistance. The newly proposed multi-attractor period multi-scroll chaotic
Xin Zhang, Chunhua Wang
doaj +1 more source
New Construction of a Chaotic Generator on the Lorenz Attractor [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 it be known that the chaotic phenomena can be obtained from relatively simple systems that are governed by a small number of variables. The system will then be deterministic, although its behaviour is unforeseeable. The chaotic generator hereby suggested
Abdallah M +3 more
doaj +1 more source
Journal of High Energy Physics, 2007 43 pages, 6 figures; v2: typos and references added; v3: published version, minor ...
Gunaydin, Murat +3 more
openaire +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source