Results 71 to 80 of about 936,105 (302)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
On robust and efficient designs for risk estimation in epidemiologic studies [PDF]
We consider the design problem for the estimation of several scalar measures suggested in the epidemiological literature for comparing the success rate in two samples.
Dette, Holger
core
A strategy for bounding attributable risk: a lung cancer example. [PDF]
, 2004 In the same issue: Elizabeth Casman, Minh Ha-Duong, and M. Granger Morgan. Response to Sander Greenland's critique on bounding analysishttp://www.centre-cired.fr/perso/haduong/files/HaDuong.ea-2003-BoundingAnalysis.pdfInternational audienceFor diseases ...
Casman, Elizabeth +2 more
core +4 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Heavy work and disability pension – a long term follow-up of Swedish construction workers
Scandinavian Journal of Work, Environment & Health, 2014 OBJECTIVES: The objective of this study was to investigate the occurrence of disability pensions over time among workers with physically demanding jobs.
Bengt Järvholm +5 more
doaj +1 more source
The relation between cholesterol and haemorrhagic or ischaemic stroke in the Renfrew/Paisley study [PDF]
, 2000 Studies have found little association between cholesterol and overall stroke risk, but this could be attributable to different relations for haemorrhagic and ischaemic stroke.
Ben-Shlomo, Y. +4 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Costs of Human Salmonellosis Attributable to Pork: A Stochastic Farm-to-Fork Analysis [PDF]
Few farm-to-table analyses of the risk pathways for foodborne illnesses exist, and no such analysis exists for the case of salmonellosis and pork products.
Liu, Xuanli +2 more
core +1 more source
Lipid profile, cardiovascular disease and mortality in a Mediterranean high-risk population: The ESCARVAL-RISK study [PDF]
, 2017 Introduction The potential impact of targeting different components of an adverse lipid profile in populations with multiple cardiovascular risk factors is not completely clear.
Ascaso, Juan F +25 more
core +6 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source