Results 91 to 100 of about 614,208 (301)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Vector subscriptions and sharing mechanism for content-based publish/subscribe system

open access: yesTongxin xuebao, 2015
The concept of vector subscriptions to support subscription adaptations was introduced.Novel algorithms were proposed for updating vector subscriptions in classic matching tree structures,and was presented sharing algorithms for vector subscriptions ...
Tao YOU   +4 more
doaj  

Definition and Essence of Information

open access: yestripleC: Communication, Capitalism & Critique, 2011
It has been 60 years since the essential attributes of information were explored in the field of philosophy, resulting in many contentious schools of thought and a wide division of opinions.
Tian-qing Qiao
doaj   +1 more source

Role Attribute 1.0

open access: yes, 2012
The Role Attribute defined in this specification allows the author to annotate markup languages with machine-extractable semantic information about the purpose of an element. Use cases include accessibility, device adaptation, server-side processing, and
Birbeck, Mark   +7 more
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Comparing the performance of different approaches to deal with attribute non-attendance in discrete choice experiments: a simulation experiment [PDF]

open access: yes
There is a growing body of literature acknowledging that respondents to DCE often use simplifying strategies, like ignoring one or several attributes to provide with their choices.
Mariel Chladkova, Petr   +2 more
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Genetic Code Expansion in the Engineered Organism Vmax X2: High Yield and Exceptional Fidelity

open access: yesACS Central Science, 2021
Sebasthian Santiago González   +6 more
doaj   +1 more source

Attribute processing in environmental choice analysis: implications for willingness to pay [PDF]

open access: yes
Data from a discrete choice experiment is used to investigate the implications of failing to account for attribute processing strategies (APSs). The research was designed to elicit the economic benefits associated with landscape restoration activities ...
Campbell, Danny   +3 more
core  

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