Results 111 to 120 of about 530,734 (316)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Perceptual image attribute scales derived from overall image quality assessments [PDF]
, 2009 Psychophysical scaling is commonly based on the assumption that the overall quality of images is based on the assessment of individual attributes which the observer is able to recognise and separate, i.e. sharpness, contrast, etc. However, the assessment
Triantaphillidou, S. +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modelling and optimizing multiple attribute decisions by using fuzzy sets [PDF]
The purpose of this paper is to present a coherent perspective of modeling and optimizing multiple attribute decisions by using fuzzy sets. In management practice we face most of the time the situation in which a problem have several possible solutions ...
Adina NEGRUSA, Gh. Gh. IONESCU
core
Genetic Code Expansion in the Engineered Organism Vmax X2: High Yield and Exceptional Fidelity
ACS Central Science, 2021 Sebasthian Santiago González +6 more
doaj +1 more source
, 2010 This paper investigates the concept of information. It follows different approaches for defining information before discussing a knowledge-in-action view on information as part of sociomaterial practices. Drawing from Stamper’s (1991) extended semiological framework the paper proposes its reinterpretation to study information as a sociomaterial ...
Boell, Sebastian K +1 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Attribute-based signatures with efficient revocation [PDF]
, 2013 Based signatures (ABS for short) allow an entity to sign messages with a fine-grained control over identity information. The signature attests not to the identity of the individual who endorsed a message, but instead to a claim regarding the attributes ...
Y Lian (11424984) +2 more
core
Notre Dame Journal of Formal Logic, 1978 In this paper it is argued that proper names, like definite descriptions, have attributive as well as referential uses. The reasons given for countenancing attributive definite descriptions are shown to apply, mutatis mutandis, to the case of names. The advantages of recognizing attributive employments of names are at least twofold: On the one hand, it
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source