Results 51 to 60 of about 30,518 (252)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Motif-Preserving Dynamic Attributed Network Embedding
Proceedings of the Web Conference 2021, 2021 Network embedding has emerged as a new learning paradigm to embed complex network into a low-dimensional vector space while preserving node proximities in both network structures and properties. It advances various network mining tasks, ranging from link prediction to node classification.
Zhijun Liu +3 more
openaire +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
SpecRp: A spectral-based community embedding algorithm
Machine Learning with Applications, 2022 Community embeddings are useful in node classification since they allow nodes to aggregate relevant information regarding the network structure. Modularity maximization-based algorithms are the most common approach to detect communities in networks ...
Camila P.S. Tautenhain +1 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
QoS Prediction of Web Services Based on Reputation-Aware Network Embedding
IEEE Access, 2020 As the emergence of numerous services with similar functions, it is very helpful to recommend personalized services for users, and urgent to accurately predict the QoS(Quality-of-Service) values of Web services. Collaborative Filtering (CF) is a commonly-
Xuechun Wang +3 more
doaj +1 more source
IEEE Access, 2022 A significant aspect of today’s digital information is attributed networks, which combine multiple node attributes with the basic network topology to extract knowledge.
Wasim Khan +6 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
CAAI Transactions on Intelligence Technology, 2023 Contrastive self‐supervised representation learning on attributed graph networks with Graph Neural Networks has attracted considerable research interest recently. However, there are still two challenges.
Beibei Han +3 more
doaj +1 more source