Results 91 to 100 of about 2,747,349 (267)
Modeling Social Networks with Node Attributes using the Multiplicative Attribute Graph Model [PDF]
, 2011 Networks arising from social, technological and natural domains exhibit rich connectivity patterns and nodes in such networks are often labeled with attributes or features.
Kim, Myunghwan, Leskovec, Jure
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The role and attributes of entrepreneurs at South Africa’s largest arts festival.
PASOS Revista de Turismo y Patrimonio Cultural, 2009 The Klein Karoo National Arts Festival (KKNK) in Oudtshoorn, South Africa, is the largest arts festival in South Africa. The purpose of this research was to determine the attributes and role of the entrepreneurs at the Klein Karoo National Arts Festival.
E. Jonker, M. Saayman, S. de Klerk
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A new perspective on the Walser community:
Revue de Géographie Alpine, 2009 This paper focuses on an INTERREG IIIB project to conserve and promote the so-called Walser culture. The case study shows how different stakeholders are involved in a network that transcends national borders.
Mathieu Petite
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Infrastructures, 2018 The concept of Smart City aims to provide its citizens with infrastructure systems that make cities safer and more livable. One of the methods for doing so is collecting data from the crowd itself—termed crowdsourcing—and incorporating their ideas to ...
Parul Srivastava, Ali Mostafavi
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Revista UIS Ingenierías, 2019 This paper presents a comparative study of the measurement features used as inputs of a fault locator based on Support Vector Machines, which is aimed to analyze single-phase faults.
Ever Correa-Tapasco +2 more
doaj +1 more source