Results 91 to 100 of about 3,278,147 (276)

Attribution of the impacts of the 2008 flooding in Cedar Rapids (Iowa) to anthropogenic forcing

open access: yesEnvironmental Research Letters, 2020
The City of Cedar Rapids was significantly affected by the June 2008 flood. However, little is known about the role anthropogenic warming during this event, not only in terms of hydrologic response but also of impacts.
Gabriele Villarini   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An exploration of pre-service teachers’ attributions in English

open access: yesSHS Web of Conferences, 2016
With the developments in cognitive psychology, language learners’ beliefs have received considerable attention in the domain of language teaching and learning.
Yılmaz Cevdet
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

„Oblężenie i obrona Saragossy” Józefa Mrozińskiego a tradycja narracji heroicznej

open access: yesStylistyka, 2019
The detailed studies conducted in the article are based on the issue of heroic narrative. Heroic narrative is a type of writing concerning serious subjects significant to the Polish identity, cultural context and national history.
MARZANNA UŹDZICKA
doaj  

A Theory of Attribution [PDF]

open access: yes
Attribution of economic joint effects is achieved with a random order model of their relative importance. Random order consistency and elementary axioms uniquely identify linear and proportional marginal attribution.
Feldman, Barry
core   +1 more source

Apsines and Pseudo-Apsines (Attribution of Greek rhetorical treatises) [PDF]

open access: yes, 1998
Citations of Apsines by name in the treatise transmitted under his name are inconsistent with the traditional attribution. Editors remove the problem by treating these citations as interpolations, but there is no text-critical warrant for this.
Heath, M.
core  

Multi-Touch Attribution Based Budget Allocation in Online Advertising

open access: yes, 2014
Budget allocation in online advertising deals with distributing the campaign (insertion order) level budgets to different sub-campaigns which employ different targeting criteria and may perform differently in terms of return-on-investment (ROI).
Dasdan, Ali   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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