Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
On the attribution of externalities [PDF]
Do people blame or praise others for producing negative or positive externalities? The experimental philosopher Knobe conducted a questionnaire study that revealed that people blame others for foreseen negative externalities but do not praise them for ...
Urs Fischbacher, Verena Utikal
core
The role of unusual conscious experiences in mental illness : an exploration guided by process models of symptom formation and by a hierarchical theory of personal illness : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
The relationship between non-clinical unusual conscious experiences and mental illness was explored cross-sectionally in 104 users of community mental health services.
Barclay, John Craster
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Explain Your Move: Understanding Agent Actions Using Specific and Relevant Feature Attribution [PDF]
Nikaash Puri +6 more
openalex +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Understanding Everyday Mental Concepts: Theory or Simulation? [PDF]
In the course of explaining and anticipating thought and action, we characterize both ourselves and others in mental terms, e.g. as "believing the bus departs at ten" or "wanting to go swimming".
Röska-Hardy, Lousie
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Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CORRELATION OF THE TERMS "CLASSIFICATION ATTRIBUTE", "MOTIVATIONAL ATTRIBUTE", "SEMANTIC ATTRIBUTE"
The problem of distinguishing the terms "classification attribute", "motivational attribute", "semantic attribute" arose in connection with the active development of cognitive linguistics and the expansion of its terminology. The article describes for the first time approaches to understanding terms in a comparative aspect.
openaire +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

