Results 141 to 150 of about 46,848 (253)

Antipsychotic Drug Use: Managing Cardiometabolic and Cost Effects [PDF]

open access: yes, 2018
Across the US, 30%, or approximately one third of people meet the criteria for at least one mental illness.1 Of those with severe mental illness (SMI), namely schizophrenia and bipolar disorder, the mortality rate is more than twofold compared to the ...
Braga, Olivia G
core   +1 more source

Agitation in Nonverbal Patients With Autism: The Role of Sensory Evaluation in Diagnosis and Management

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental condition often associated with communication barriers, sensory sensitivities, and behavioral challenges, including agitation. Identifying the underlying causes of acute agitation in nonverbal individuals with ASD can be difficult, leading to diagnostic delays and unnecessary ...
Logan Bailey   +4 more
wiley   +1 more source

Barriers to long‐acting injectable atypical antipsychotic use in Japan: Insights from a comparative psychiatrist survey

open access: yesNeuropsychopharmacology Reports
Aims To investigate the negative attitudes of Japanese psychiatrists toward atypical long‐acting injectable (LAI) antipsychotics, which are the current mainstream LAIs in Japan.
Yoshiyo Oguchi   +2 more
doaj   +1 more source

Addressing Behavioral and Psychiatric Symptoms in Dystonia: A Case Report of Fahr Disease

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Abnormal calcium deposits in areas of the brain that control movement, including basal ganglia and cerebellum, are the hallmark of Fahr's syndrome. This report highlights the importance of clinicians being vigilant regarding behavioral and neuropsychiatric symptoms when evaluating cases of dystonia.
Tara Khoeini, Mohammad Javad Sinaeefar
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Lipid profile in schizophrenic patients on atypical antipsychotics

open access: yesGomal Journal of Medical Sciences, 2012
Background: Atypical antipsychotics are the drugs of first line treatment in schizophrenia because compared to typical antipsychotics, they have minimum extrapyramidal side effects and hence better tolerance by the patients resulting in better compliance.
Faiz ur Rahman   +3 more
doaj  

Racial and Ethnic Representation in Dementia Clinical Trials Registered on ClinicalTrials.gov in the United States, United Kingdom, and Canada

open access: yesInternational Journal of Geriatric Psychiatry, Volume 41, Issue 5, May 2026.
ABSTRACT Objective To evaluate racial and ethnic representation and temporal trends in phase II–IV dementia clinical trials conducted in the United States, United Kingdom, and Canada. Methods We interrogated ClinicalTrials.gov for interventional dementia and Alzheimer's disease (AD) trials completed since 2000.
Daniel Kramarczyk   +6 more
wiley   +1 more source

Efficacy of Dextromethorphan Augmentation in SSRI‐Resistant Obsessive–Compulsive Disorder: A Randomized Controlled Trial

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Obsessive–compulsive disorder (OCD) is a chronic condition associated with marked functional impairment and high rates of treatment resistance. Converging evidence implicates glutamatergic dysregulation in OCD pathophysiology.
Ahmad Zolghadriha   +2 more
wiley   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

open access: yesPhytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli   +4 more
wiley   +1 more source

Dietary Quality in Bipolar Disorder Compared to Unipolar Depression (Current and Remitted) and Healthy Controls: The Netherlands Study of Depression and Anxiety

open access: yesBipolar Disorders, Volume 28, Issue 3, May 2026.
ABSTRACT Background Patients with bipolar disorder (BD) have an increased risk to develop cardiovascular disease. Western diets have been hypothesized to increase the risk of cardiovascular disease in BD, but dietary habits in BD have not been extensively studied.
M. A. Riedinger   +7 more
wiley   +1 more source

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