Results 141 to 150 of about 28,403 (261)

The safety of atypical antipsychotics in pregnancy

open access: yes, 2004
Three studies were conducted. (1) A retrospective review of the Motherisk Clinic appointments determined that there was an increase in the proportion of appointments for antipsychotics each year since the introduction of atypicals.
McKenna, Kathleen Danielle
core  

Learning Outcomes That Maximally Differentiate Psychiatric Treatments

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives To develop a statistical method that uncovers clinically meaningful differences between active psychiatric treatments, even when traditional rating scales fail to do so. Methods We introduce Supervised Varimax (SV), a novel algorithm that transforms individual items from clinical rating scales into a small set of optimized outcomes ...
Eric V. Strobl, Semmie Kim
wiley   +1 more source

MicroRNAs in metabolic effects with atypical antipsychotics-a scoping review. [PDF]

open access: yesTher Adv Psychopharmacol
Wu WT   +4 more
europepmc   +1 more source

Japanese Cohort Study and Meta‐Analysis Demonstrate Significant Association Between Serotonin Transporter‐Linked Polymorphic Region and Schizophrenia

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This study demonstrates a significant association between the 5‐HTTLPR polymorphism and schizophrenia risk. The short allele was significantly overrepresented in patients (OR = 1.39, p = 0.007), suggesting a potential contribution to schizophrenia risk.
Masao Miyachi   +8 more
wiley   +1 more source

Prolactin response with typical and atypical antipsychotics

open access: yes, 2000
grantor: University of Toronto'Introduction'. Evidence suggests that, unlike typical antipsychotics, 'atypicals' spare the prolactin (PRL) secreting system.
Turrone, Peter
core   +1 more source

Effects of Repeated Smoking and Quitting Cigarettes on Plasma Concentrations of Clozapine and Its N‐Desmethyl and N‐Oxide Metabolites in a Japanese Patient With Schizophrenia

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
In a Japanese patient with schizophrenia, the effects of repeated smoking and quitting cigarettes on plasma concentrations of clozapine (CLZ) and its major metabolites, N‐desmethyl clozapine (NCLZ) and N‐oxide clozapine (OCLZ), were shown to be reproducible. ABSTRACT Clozapine (CLZ) is used for treatment‐resistant schizophrenia.
Kazuro Ikawa   +3 more
wiley   +1 more source

Prescribing and deprescribing of atypical antipsychotics in older multimorbid patients. [PDF]

open access: yesBMC Geriatr
Schneider C   +8 more
europepmc   +1 more source

Pharmacological Management, Safety, and Outcomes in Bipolar Disorder: An Integrated Narrative Review of Clinical and Translational Evidence

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This graph summarizes bipolar disorder management, showing pharmacological treatments including lithium, valproate, antipsychotics, combination therapy, and emerging agents. It links these treatments to outcomes such as relapse reduction, mortality benefits, and cognitive effects, while highlighting safety issues, poor adherence, pregnancy risks, and ...
Gudisa Bereda
wiley   +1 more source

Comparing the side effect profile of the atypical antipsychotics.

open access: yes, 2002
Typical antipsychotics exert their effect by blocking post-synaptic dopaminergic receptors; blockade of the mesolimbic and mesocortical pathways are therapeutic and help reduce positive psychotic symptoms but blockade of the nigro-striatal pathway ...
Malhotra, Kamna   +2 more
core  

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