Atypical Hemolytic Uremic Syndrome
Kaan GÜLLEROĞLU +2 more
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The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease [PDF]
Atypical hemolytic uremic syndrome (aHUS) is characterized by complement attack against host cells due to mutations in complement proteins or autoantibodies against complement factor H (CFH).
Abarrategui-Garrido +59 more
core +1 more source
Atypical hemolytic uremic syndrome (aHUS) is a clinical diagnosis characterized by a triad of microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. Postoperative aHUS in nontransplant patients is a rare entity.
Anil Khetarpal +2 more
doaj +1 more source
FHR-1 binds to C-reactive protein and enhances rather than inhibits complement activation [PDF]
Factor H (FH)-related protein 1 (FHR-1) is one of the five human factor H-related proteins, which share sequence and structural homology with the alternative pathway complement inhibitor FH.
Bánlaki, Zsófia +7 more
core +1 more source
Atypical hemolytic-uremic syndrome, manifesting without thrombocytopenia (clinical case)
Background. Atypical hemolytic uremic syndrome is an ultra-rare (orphan) disease from the group of thrombotic microangiopathies of progressive course, which is caused by uncontrolled activation of the alternative complement pathway of hereditary or ...
A.A. Dyachkova +3 more
doaj +1 more source
Concurrent Atypical Hemolytic Uremic Syndrome and Autoimmune Hemolytic Anemia: a case report
Background: Atypical hemolytic uremic syndrome (aHUS) is a life-threatening and scarce disorder characterized by acute renal failure and disease, non-immune microangiopathic hemolytic anemia and thrombocytopenia, leading to end-stage renal failure or ...
Sayed Yousef Mojtahedi +1 more
doaj
Successful long-term outcome after renal transplantation in a patient with atypical haemolytic uremic syndrome with combined membrane cofactor protein CD46 and complement factor I mutations [PDF]
Background: Atypical haemolytic uremic syndrome (aHUS) is often associated with a high risk of disease recurrence and subsequent graft loss after isolated renal transplantation.
Bresin, Elena +5 more
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Administração profiláctica de plasma no síndrome hemolítico urémico atípico recorrente [PDF]
O síndrome hemolítico urémico (SHU) define- se pela ocorrência simultânea de anemia hemolítica microangiopática, trombocitopenia e insuficiência renal aguda.
Almeida, Marta Pinto de +7 more
core
Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]
, +4 more
core +1 more source
The role of complement in Streptococcus pneumoniae-associated haemolytic uraemic syndrome [PDF]
Background. Atypical forms of haemolytic uraemic syndrome (aHUS) include HUS caused by defects in the regulation of alternative complement pathway and HUS linked to neuraminidase- producing pathogens, such as Streptococcus pneumoniae. Increasing data
Szilágyi, Ágnes
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