Aim. To evaluate the effectiveness of the intrauterine levonorgestrel-releasing device (LNG-IUD) in the treatment of atypical hyperplasia and the use of LNG-IUD in combination with a gonadotropin-releasing hormone analog (3.6 mg goserelin depot) in the ...
Lyubov T. Gadzhieva+4 more
doaj +1 more source
BackgroundTo inform treatment decisions in women diagnosed with endometrial hyperplasia, quantification of the potential for concurrent endometrial cancer and the future risk of progression to cancer is required.MethodsWe identified studies up to ...
Michelle T Doherty+7 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
A Potential Invasion-Promoting Role for Ezrin in Endometrial Carcinoma [PDF]
Background:Ezrin is a cell membrane-cytoskeleton linker that is essential to maintain the normal cell shape and the integrity of cell-cell adhesion. Overexpression of ezrin is correlated with poor prognosis in several malignancies.
Ahmed R. H. Ahmed+3 more
doaj +1 more source
The reproductive function of patients with prior atypical endometrial hyperplasia and endometrial cancer treatment: cohort study [PDF]
Aim. To define the management of realization of reproductive function implementation in patients experienced atypical endometrial hyperplasia and endometrial cancer IA stage. Materials and methods. 150 patients aged 2142 years were included.
Lana G. Dzhanashvili+4 more
doaj +1 more source
Prevalence of incidental breast cancer and precursor lesions in autopsy studies: A systematic review and meta-analysis [PDF]
Background Autopsy studies demonstrate the prevalence pool of incidental breast cancer in the population, but estimates are uncertain due to small numbers in any primary study.
Barratt, Alexandra+5 more
core +2 more sources
Atypical Ductal Hyperplasia at the Margin of Lumpectomy Performed for Early Stage Breast Cancer: Is there Enough Evidence to Formulate Guidelines? [PDF]
Background. Negative margins are associated with a reduced risk of ipsilateral breast tumor recurrence (IBTR) in women with early stage breast cancer treated with breast conserving surgery (BCS).
Baker, Jennifer L+2 more
core +3 more sources
Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study. [PDF]
BackgroundLobular endocervical glandular hyperplasia (LEGH) is a rare lesion of the uterine cervix. It has been proposed that LEGH may represent a precursor lesion to a group of mucinous adenocarcinoma with gastric phenotype (GA) that is independent of ...
Carter, R+9 more
core +1 more source
Promotion of the occurrence of endometrioid carcinoma by S100 calcium binding protein P
Background Endometrial cancer, one of the most common malignant tumors, is a serious threat to women’s health. Endometrial hyperplasia is a precursor of endometrial cancer.
Dan Zhang+7 more
doaj +1 more source
Preleukemia: hematological disorders prior to onset of leukemia [PDF]
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Hiraki, Kiyoshi+5 more
core +1 more source