Results 51 to 60 of about 67,280 (286)

CEUS LI-RADS: a pictorial review [PDF]

, 2020
Contrast-enhanced ultrasound (CEUS) greatly improved the diagnostic accuracy of US in the detection and characterization of focal liver lesions (FLLs), and it is suggested and often included in many international guidelines as an important diagnostic ...
Bartolotta, Tommaso Vincenzo, Gagliardo, Cesare, Taibbi, Adele, Terranova, Maria Chiara   +3 more
core   +1 more source

Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study
Luigi Nappi, Stefano Angioni, Vincenzo De Feo, Pantaleo Greco, Guglielmo Stabile, Francesca Greco, Maurizio Nicola D'Alterio, Felice Sorrentino   +7 more
doaj   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Digital morphometry of cytologic aspirate endometrial samples [Digitalna morfometrijska analiza citoloških uzoraka aspirata endometrija] [PDF]

, 2010
Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for.
Babić, Damir, Barišić, Ana, Božikov, Jadranka, Ilić-Forko, Jadranka, Jurič, Danijela, Mahovlić, Vesna, Ovanin-Rakić, Ana, Rajhvajn, Sanda, Šamija Projić, Ivana, Škopljanac-Mačina, Lada, Škrablin-Kučić, Snježana   +10 more
core  

Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21^WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]

, 2008
To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Alexander, C.L., Chan, W-C., Greenhalgh, D.A., Quinn, J., Wu, H., Yao, D.   +5 more
core   +1 more source

Changes in mRNA expression of oncogenesis driver genes in atypical ductal breast hyperplasia

Опухоли женской репродуктивной системы
Background. Atypical ductal hyperplasia is a relatively common breast lesion that increases the risk of breast cancer by 3.5 to 5 times. Genomic rearrangements underlying the development of atypical proliferative lesions and breast cancer lead to gene ...
O. V. Burmenskaya, V. V. Kometova, A. A. Smetnik, V. V. Rodionov, D. Yu. Trofimov, L. A. Ashrafyan, G. T. Sukhikh   +6 more
doaj   +1 more source

Conservative Management of Atypical Endometrial Hyperplasia and Early Endometrial Cancer in Childbearing Age Women

Medicina, 2022
Total hysterectomy and bilateral adnexectomy is the standard treatment for atypical endometrial hyperplasia and early-stage endometrial cancer. However, the recommended surgical treatment precludes future pregnancy when these conditions are diagnosed in ...
Stefano Uccella, Pier Carlo Zorzato, Susan Dababou, Mariachiara Bosco, Marco Torella, Andrea Braga, Matteo Frigerio, Barbara Gardella, Stefano Cianci, Antonio Simone Laganà, Massimo Piergiuseppe Franchi, Simone Garzon   +11 more
doaj   +1 more source

Expert Perspectives on a Clinical Challenge: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, Accepted Article.
Systemic vasculitis describes a collection of rare diseases each caused by inflammation of blood vessel walls that can cause severe systemic complications [[3, 4]](#ref‐0003). The pattern of vascular inflammation and resultant damage is frequently variable and may be mimicked, or directly triggered, by infection or malignancy.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Novel associations in disorders of sex development: findings from the I-DSD registry [PDF]

, 2013
Context: The focus of care in disorders of sex development (DSD) is often directed to issues related to sex and gender development. In addition, the molecular etiology remains unclear in the majority of cases.<p></p> Objective: To report ...
Ahmed, Ahmed, Ahmed, Ahmed, Akre, Antonio Balsamo, Bangsbøll, Bebermeier, Berger, De Groote, Dolk, Duguid, Feyza Darendeliler, Flück, Gottlieb, Guerrier, Hiort, Hughes, Hughes, Hughes, Ieuan Hughes, Jillian Bryce, Jipu Jiang, Kathryn Cox, Kreidberg, Köhler, Laura Audi, Lidka Lisa, Martina Rodie, Martine Cools, Melià, Miles, Mona Alkhawari, Mona Ellaithi, Morcel, Nabhan, Nils Krone, Nowaczyk, Olaf Hiort, Olle Soder, Ono, Pang, Paul-Martin Holterhus, Peter Wieacker, Porter, Richard Sinnott, S. Faisal Ahmed, Silvano Bertelloni, Stenvert Drop, Sun, Telvi, Thyen, Tokgoz, Tosson, Tulay Guran, Wiebke Arlt, Yang, Yinon, Yves Morel   +58 more
core   +3 more sources

Ibuprofen Induces Reduction of the Proliferation-Seeking Radiotracer Tc-(V)DMSA Uptake in Severe Epithelial Breast Hyperplasia without Atypia

Molecular Imaging, 2010
The purpose of this study was to investigate if ibuprofen intake can influence mammary uptake of the proliferation-seeking radiotracer technetium 99m–pentavalent dimercaptosuccinic acid ( 99m Tc-(V)DMSA) in women with severe epithelial and atypical ...
Vassilios Papantoniou, Angeliki Tsaroucha, Pipitsa Valsamaki, Spyridon Tsiouris, Evangelia Sotiropoulou, Theodore Karianos, Spyridon Marinopoulos, Athina Fothiadaki, Maria Sotiropoulou, Aikaterini Archontaki, Konstantinos Syrgiannis, Konstantinos Dimitrakakis, Aris Antsaklis   +12 more
doaj   +1 more source