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Abstract 6265: FLCN variants and their role in parathyroid cancer and atypical parathyroid tumors

Cancer Research
Abstract Parathyroid carcinoma (PC) is rare, poses challenges in definitive diagnosis and treatment, and carries a high rate of recurrence and mortality. Atypical parathyroid tumors (APT) have histopathologic features of malignancy but lack unequivocal evidence of invasion and are of uncertain malignant potential.
Callie Burke   +3 more
openaire   +1 more source

Preoperative CALLY Index for Identifying Atypical Parathyroid Tumors

Clinical Endocrinology
ABSTRACT Background Atypical parathyroid tumors (APTs) are diagnostically challenging neoplasms that display worrisome histopathological features but do not meet the criteria for carcinoma. Conventional biochemical and imaging parameters have limited discriminatory accuracy, and no validated ...
Rıza Deryol   +4 more
openaire   +1 more source

Calcaneal brown tumor with primary hyperparathyroidism caused by parathyroid carcinoma: An atypical localization

The Journal of Foot and Ankle Surgery, 2004
Brown tumors are one of the characteristics of primary hyperparathyroidism, although, in some cases, they are noted with secondary hyperparathyroidism as well. The authors present a case of a 50-year-old woman with primary hyperparathyroidism caused by parathyroid carcinoma with an unusual location of a brown tumor in the calcaneus. She first presented
Ali, Doğan   +5 more
openaire   +2 more sources

A rare case of atypical parathyroid tumor with atypical presentation

Endocrine Abstracts, 2023
Thant Aye Aye, Alexander Lewis
openaire   +1 more source

Whole-exome Sequencing of Atypical Parathyroid Tumors Detects Novel and Common Genes Linked to Parathyroid Tumorigenesis

The Journal of Clinical Endocrinology & Metabolism
Abstract Context Atypical parathyroid tumor (APT) represents a neoplasm characterized by histological features typical of parathyroid carcinoma (PC) but lacking local infiltration and/or distant metastasis, leading to uncertainty regarding its malignant potential.
Elena Pardi   +7 more
openaire   +3 more sources

The role of immunohistochemical examination in the differential diagnosis of atypical tumors and carcinomas of parathyroid glands

Russian Journal of Archive of Pathology
Differential diagnosis of atypical parathyroid tumors (APT) and parathyroid carcinomas (PC) is important in determining further management and prognosis. Morphologic diagnosis is sometimes difficult, in which case it is supplemented by immunohistochemical (IHC) examination. Objective.
E.I. Kim   +5 more
openaire   +2 more sources

Parathyroid Carcinoma Mimicking Thyroid Hyalinizing Trabecular Tumor: A Case Report and Review of Atypical Presentations of Parathyroid Carcinoma

International Journal of Surgical Pathology
We present a parathyroid carcinoma with hyalinizing trabecular architecture and a prominent spindle-cell component. The tumor closely mimicked a hyalinizing trabecular tumor of the thyroid due to its trabecular growth, eosinophilic hyalinized stroma, and nuclear features including grooves and intranuclear pseudoinclusions.
Paola Loreto-Palacio   +3 more
openaire   +2 more sources

A Rare Atypical Parathyroid Tumor In Young Adult Man : A Diagnostic Challenge

International Journal of Drug Delivery Technology
Parathyroid carcinoma (PC), an extremely rare endocrine malignancy, was found to coexist synchronously with papillary thyroid carcinoma (PTC) in a 23-year-old male, presenting a unique and complex case. The patient displayed signs of severe primary hyperparathyroidism, including weakness, bone pain, and weight loss, supported by severe hypercalcemia ...
Leonard Alen Melatunan   +1 more
openaire   +1 more source

Clinical Utility of Solid Tumor Epigenetics

Medical Epigenetics, 2021
Sevin Turcan, Julian Taranda
exaly  

Brain and Other Central Nervous System Tumor Statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Rebecca L. Siegel   +2 more
exaly  

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