Results 101 to 110 of about 795,158 (288)
New insights into cochlear sound encoding [version 1; referees: 2 approved]
F1000Research, 2016 The inner ear uses specialized synapses to indefatigably transmit sound information from hair cells to spiral ganglion neurons at high rates with submillisecond precision.
Tobias Moser, Christian Vogl
doaj +1 more source
Management of tegmen defects with mastoid and epitympanic obliteration using S53P4 bioactive glass
Laryngoscope Investigative Otolaryngology, 2020 Objective To evaluate the surgical results and complications in a cohort of patients operated on to repair a tegmen bony defect using either transmastoid approach with obliteration using S53P4 bioactive glass granules (TMA‐O), or the classic middle ...
Françoise Remangeon +7 more
doaj +1 more source
Advanced Science, EarlyView.Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin +10 more
wiley +1 more source
Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS
Advanced Science, EarlyView.ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi +4 more
wiley +1 more source
Nature Communications, 2017 The changes that accompany age-related decreases in speech comprehension are not yet understood. Here, authors show that older adults are less able to entrain to speech-paced auditory rhythms and that the behavioural consequences can be counteracted by ...
Molly J. Henry +3 more
doaj +1 more source
Relating age and hearing loss to monaural, bilateral, and binaural temporal sensitivity
Frontiers in Neuroscience, 2014 Older listeners are more likely than younger listeners to have difficulties in making temporal discriminations among auditory stimuli presented to one or both ears.
Frederick J. Gallun +9 more
doaj +1 more source
, 2017 We present AudExpCreator, a GUI-based Matlab tool for designing and creating auditory experiments. AudExpCreator allows users to generate auditory experiments that run on Matlab's Psychophysics Toolbox without having to write any code; rather, users ...
Kaneshiro, Blair, Nguyen, Duc T.
core +1 more source
Advanced Science, EarlyView.Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Frontiers in Neural Circuits, 2019 The reduction of neuronal responses to repeated stimulus presentation occurs in many sensory neurons, also in the inferior colliculus of birds. The cellular mechanisms that cause response adaptation are not well described.
Sebastian T. Malinowski +3 more
doaj +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source