Results 61 to 70 of about 804,947 (306)

Neural Dynamics of Phonological Processing in the Dorsal Auditory Stream [PDF]

, 2013
Neuroanatomical models hypothesize a role for the dorsal auditory pathway in phonological processing as a feedforward efferent system (Davis and Johnsrude, 2007; Rauschecker and Scott, 2009; Hickok et al., 2011).
Beardsley, Scott A., Desai, Anjali, Liebenthal, Einat, Mangalathu-Arumana, Jain, Sabri, Merav   +4 more
core   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities

EMBO Molecular Medicine
Optogenetics allows versatile control of excitable cell networks, which advances basic science research and drives the development of future medical applications.
Lennart Roos, Aida Garrido-Charles, Niels Albrecht, Anna Vavakou, Alexey Alekseev, Martina Bleyer, Anupriya Thirumalai, Artur Mittring, Theocharis Alvanos, Antoine T Huet, Ernst Bamberg, Kathrin Kusch, Bettina J Wolf, Tobias Moser, Thomas Mager   +14 more
doaj   +1 more source

CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells

eLife
To encode continuous sound stimuli, the inner hair cell (IHC) ribbon synapses utilize calcium-binding proteins (CaBPs), which reduce the inactivation of their CaV1.3 calcium channels. Mutations in the CABP2 gene underlie non-syndromic autosomal recessive
David Oestreicher, Shashank Chepurwar, Kathrin Kusch, Vladan Rankovic, Sangyong Jung, Nicola Strenzke, Tina Pangrsic   +6 more
doaj   +1 more source

Effects of congenital hearing loss and cochlear implantation on audiovisual speech perception in infants and children [PDF]

, 2010
Purpose: Cochlear implantation has recently become available as an intervention strategy for young children with profound hearing impairment. In fact, infants as young as 6 months are now receiving cochlear implants (CIs), and even younger infants are ...
Bergeson, Tonya R., Houston, Derek M., Miyamoto, Richard T.   +2 more
core   +2 more sources

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Sex differences in auditory processing vary across estrous cycle

Scientific Reports, 2021
In humans, females process a sound’s harmonics more robustly than males. As estrogen regulates auditory plasticity in a sex-specific manner in seasonally breeding animals, estrogen signaling is one hypothesized mechanism for this difference in humans. To
Jennifer Krizman, Elena K. Rotondo, Trent Nicol, Nina Kraus, Kasia Bieszczad   +4 more
doaj   +1 more source

Auditory corticofugal neurons transmit auditory and non-auditory information during behavior

The Journal of Neuroscience, 2022
AbstractLayer 5 pyramidal neurons of sensory cortices project “corticofugal” axons to myriad sub-cortical targets, thereby broadcasting high-level signals important for perception and learning. Recent studies suggestdendritic Ca2+spikesas key biophysical mechanisms supporting corticofugal neuron function: These long-lasting events drive burst firing ...
Alexander N. Ford, Jordyn E. Czarny, Meike M. Rogalla, Gunnar L. Quass, Pierre F. Apostolides   +4 more
openaire   +2 more sources

Neonatal Cortical Auditory Evoked Potentials Are Affected by Clinical Conditions Occurring in Early Prematurity [PDF]

, 2015
Purpose: Cortical auditory evoked potentials may serve as an early indicator of developmental problems in the auditory cortex. The aim of the study was to determine the effect on neonatal cortical auditory processing of clinical conditions occurring in ...
Bisiacchi, Patrizia, Cainelli, Elisa, Cappellari, Ambra, Ermani, Mario, Sartori, Stefano, Suppiej, Agnese   +5 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source