Results 131 to 140 of about 141,996 (298)

Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The purpose of this study is to identify the earliest appearing auditory electrophysiological indicators that change with age progression in young adults with normal hearing, and to analyze the frequency distribution patterns of these markers in the cochlear.
Min‐Fei Qian   +6 more
wiley   +1 more source

Severe Hearing Loss in the World's First Successfully Captive‐Born Yangtze Finless Porpoise: Impact of High Underwater Sound Exposure and Congenital Hearing Disorders

open access: yesIntegrative Zoology, EarlyView.
The audiogram of the world's first successfully captive‐born Yangtze finless porpoise was on average 40 dB higher than conspecifics. Congenital hearing disorders and noise exposure may be the primary cause of porpoise's hearing loss. ABSTRACT Aquariums globally have seen significant growth in recent decades.
Zhitao Wang   +3 more
wiley   +1 more source

Chronic Low‐Level Lead Exposure Causes Auditory Impairment and Accelerates the Progression of Age‐Related Hearing Loss in C57BL/6J Mice

open access: yesAging Cell, EarlyView.
Chronic low‐concentration lead exposure accelerates the development of ARHL. Lead exposure mediates damage to cochlear sensory cells via the mitochondrial protease LONP1, leading to irreversible hearing loss. ABSTRACT Heavy metal ion exposure has become a global public health concern.
Xue Bai   +10 more
wiley   +1 more source

Soma-Axon Coupling Configurations That Enhance Neuronal Coincidence Detection [PDF]

open access: yes, 2019
Coincidence detector neurons transmit timing information by responding preferentially to concurrent synaptic inputs. Principal cells of the medial superior olive (MSO) in the mammalian auditory brainstem are superb coincidence detectors.
Goldwyn, Joshua H.   +2 more
core   +1 more source

Optochemical modulation of corneal cold nerve terminal impulse activity with a photochromic ion channel blocker

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The functional organization of corneal cold nerve endings, critical structures in maintaining the ocular surface, remains poorly understood. Here, the photoisomerizable small‐molecule diethylamine‐azobenzene‐quaternary ammonium (DENAQ) was used to photomodulate activity of cold‐sensing nerve terminals in control and chronic tear ...
David Ares‐Suárez   +11 more
wiley   +1 more source

fNIRS vs. EEG in audiological diagnostics: novel approaches to recording brain responses to auditory stimulation

open access: yesFrontiers in Medicine
BackgroundElectroencephalography (EEG) is the traditional method for Auditory Evoked Potentials (AEPs) like Brainstem Auditory Evoked Response (BERA), offering excellent temporal resolution but facing limitations in portability and patient comfort.
Tomas Mimra   +2 more
doaj   +1 more source

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

open access: yesCell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang   +10 more
wiley   +1 more source

Functional implications of Cav2.3 R‐type voltage‐gated calcium channels in the murine auditory system – novel vistas from brainstem‐evoked response audiometry [PDF]

open access: hybrid, 2019
Andreas Lundt   +13 more
openalex   +1 more source

Temporohyoid osteoarthropathy presenting as unilateral epistaxis in a mare

open access: yesEquine Veterinary Education, EarlyView.
Summary An 18‐year‐old Selle Français mare presented with recurrent mild left‐sided epistaxis. Guttural pouch endoscopy revealed multiple focal mucosal erosions and congested vasculature overlying an enlarged left temporohyoid joint (THJ), and standing cone beam computed tomography (CBCT) confirmed moderate left‐sided temporohyoid osteoarthropathy (THO)
S. E. Sage   +4 more
wiley   +1 more source

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