Post-training load-related changes of auditory working memory: An EEG study [PDF]
Working memory (WM) refers to the temporary retention and manipulation of information, and its capacity is highly susceptible to training. Yet, the neural mechanisms that allow for increased performance under demanding conditions are not fully understood.
Bruns, P. +6 more
core +2 more sources
Auditory Cortex: Representation through Sparsification? [PDF]
SummaryThe recent discovery of combination-sensitive neurons in the primary auditory cortex of awake marmosets may reconcile previous, apparently contradictory, findings that cortical neurons produce strong, sustained responses, but also represent stimuli sparsely.
Willmore, B, King, A
openaire +3 more sources
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller +3 more
wiley +1 more source
Background: Hemispheric asymmetry is a fundamental feature of the human brain. Numerous studies on auditory functions have shown both structural and functional differences between the left and right auditory cortex in the superior temporal gyrus (STG ...
Sarah Lambelin +4 more
doaj +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Modulation of auditory responses by modality-specific attention in rat primary auditory cortex [PDF]
How does attention modulate sensory representations? In order to probe the underlying neural mechanisms, we established a simple rodent model of modality-specific attention.
Anthony M. Zador, Lung-Hao Tai
core +2 more sources
Subicular Astrocytes Govern Seizure‐Impaired Fear Memory
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao +15 more
wiley +1 more source
A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness
Disorders of consciousness after severe brain injury are marked by reduced complexity of brain activity and limited treatment options. Using personalized whole‐brain models, this study shows that simulated lysergic acid diethylamide (LSD) and psilocybin shift patient brain dynamics closer to criticality.
Naji L.N. Alnagger +17 more
wiley +1 more source
NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats
Clinical data has confirmed that auditory impairment may be a secondary symptom of type 2 diabetes mellitus (T2DM). However, mechanisms underlying pathologic changes that occur in the auditory system, especially in the central auditory system (CAS ...
Zheng-De Du +5 more
doaj +1 more source
Review: Do the Different Sensory Areas within the Cat Anterior Ectosylvian Sulcal Cortex Collectively Represent a Network Multisensory Hub? [PDF]
Current theory supports that the numerous functional areas of the cerebral cortex are organized and function as a network. Using connectional databases and computational approaches, the cerebral network has been demonstrated to exhibit a hierarchical ...
Clemo, H. Ruth +2 more
core +2 more sources

