Results 61 to 70 of about 78,889 (298)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Visual and brainstem auditory evoked potentials in obese and overweight individuals

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Overweight and obesity are known to be associated with major health risks. Their detrimental effects on central nervous system (CNS) have begun to be appreciated too.
Sangeeta Gupta, Gaurav Gupta, Rajesh Kaiti   +2 more
doaj   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

Auditory evoked potentials in peripheral vestibular disorder individuals

International Archives of Otorhinolaryngology, 2011
Introduction: The auditory and vestibular systems are located in the same peripheral receptor, however they enter the CNS and go through different ways, thus creating a number of connections and reaching a wide area of the encephalon.
Matas, Carla Gentile, Silva, Sara Manami, Wen, Débora Dong Mei, Nunes, Cristiane da Silva, Sanches, Seisse Gabriela Gandolfi   +4 more
doaj  

Parameters for Applying the Brainstem Auditory Evoked Potential with Speech Stimulus: Systematic Review

International Archives of Otorhinolaryngology, 2017
Introduction Studies using the Brainstem Auditory Evoked Potential with speech stimulus are increasing in Brazil, and there are divergences between the methodologies used for testing. Objectives To analyze the parameters used in the study of
Luísa Bello Gabriel, Luíza Silva Vernier, Maria Inês Dornelles da Costa Ferreira, Adriana Laybauer Silveira, Márcia Salgado Machado   +4 more
doaj   +1 more source

Evaluation of N1-P2 cortical auditory evoked potential results in adult stutterers

The Egyptian Journal of Otolaryngology, 2023
Background Stuttering is a fluency disorder characterized by changes in speech flow caused by neuroaudiological factors linked to central auditory processing.
Ashraf Mahmoud Khaled, Abeir Osman Dabbous, Aisha Fawzy Abdel Hady, Dina Moustafa Abdel Sabour, Rabab Ahmed Koura   +4 more
doaj   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

A comparative study on long-term evoked auditory and visual potential responses between Schizophrenic patients and normal subjects

BMC Psychiatry, 2011
Background The electrical signals measuring method is recommended to examine the relationship between neuronal activities and measure with the event related potentials (ERPs) during an auditory and a visual oddball paradigm between schizophrenic patients
Chou Frank, Huang Min-Wei, Lo Pei-Yu, Cheng Kuo-Sheng   +3 more
doaj   +1 more source

The pain matrix reloaded: a salience detection system for the body [PDF]

, 2011
Neuroimaging and neurophysiological studies have shown that nociceptive stimuli elia salience detection system for the bodycit responses in an extensive cortical network including somatosensory, insular and cingulate areas, as well as frontal and ...
Iannetti, Gian Domenico, Legrain, Valéry, Mouraux, Andre, Plaghki, Leon   +3 more
core   +2 more sources

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source