Results 1 to 10 of about 129,029 (188)

Development of a non-human primate model for preclinical research of a novel auditory nerve implant [PDF]

Frontiers in Neuroscience
The cochlear implant is a widely available hearing restoration technology that can provide speech understanding in quiet environments. This technology struggles however, in noisy settings or situations involving multiple speakers.
Inderbir Sondh, Luke A. Johnson, Geoffrey M. Ghose, Aaron Loveland, Lisa Larson, Hubert H. Lim, Hubert H. Lim, Hubert H. Lim, Meredith E. Adams   +8 more
doaj   +2 more sources

Development of a feline model for preclinical research of a new translabyrinthine auditory nerve implant [PDF]

Frontiers in Neuroscience
Cochlear implants are among the most successful neural prosthetic devices to date but exhibit poor frequency selectivity and the inability to consistently activate apical (low frequency) spiral ganglion neurons. These issues can limit hearing performance
W. Mitchel Thomas, Steven A. Zuniga, Inderbir Sondh, Moritz Leber, Florian Solzbacher, Florian Solzbacher, Thomas Lenarz, Hubert H. Lim, Hubert H. Lim, David J. Warren, David J. Warren, Loren Rieth, Meredith E. Adams   +12 more
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Clinical value of auditory nerve enhancement in idiopathic sudden sensorineural hearing loss: a retrospective study [PDF]

Frontiers in Neurology
BackgroundThe pathogenesis of idiopathic sudden sensorineural hearing loss remains unclear, and no substantial breakthroughs have been achieved in its treatment.
Xiao Sun, Lei Chen, Lei Chen, Na Hu, Wenping Xiong, Yingjun Wang, Kunpeng Lu, Fujia Duan, Haibo Wang, Haibo Wang, Mingming Wang, Mingming Wang   +11 more
doaj   +2 more sources

The auditory nerve implant—concept and device description of a novel electrical auditory prosthesis [PDF]

Bioelectronic Medicine
The cochlear implant (CI) is considered one of the most successful neural prostheses, enabling deaf individuals to achieve intelligible speech perception.
Thomas Lenarz, Florian Solzbacher, Loren Rieth, Moritz Leber, Meredith E. Adams, Rolf Salcher, David J. Warren, Andrew J. Oxenham, Karl-Heinz Dyballa, Amir Samii, Robert K. Franklin, Waldo Nogueira, Inderbir Sondh, Abigail P. Heiller, Joseph D. Crew, Keno Huebner, Stefan Strahl, Holly A. Holman, Luke A. Johnson, Geoffrey M. Ghose, W. Mitchel Thomas, Cornelia Batsoulis, Ingeborg Hochmair, Lei Feng, Hubert H. Lim   +24 more
doaj   +2 more sources

Electrocochleography in Auditory Neuropathy Related to Mutations in the OTOF or OPA1 Gene

Audiology Research, 2021
Auditory Neuropathy (AN) is characterized by disruption of temporal coding of acoustic signals in auditory nerve fibers resulting in alterations of auditory perceptions. Mutations in several genes have been associated to the most forms of AN.
Rosamaria Santarelli, Pietro Scimemi, Chiara La Morgia, Elona Cama, Ignacio del Castillo, Valerio Carelli   +5 more
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Cervical and ocular vestibular evoked myogenic potentials test results in individuals with auditory neuropathy spectrum disorders

Audiology Research, 2013
“Auditory neuropathy spectrum disorder” is a clinical disorder where the outer hair cell functioning is intact but the functioning of the auditory nerve is affected.
Sujeet Kumar Sinha, Kruthika Shankar, R. Sharanya   +2 more
doaj   +3 more sources

Auditory cortex basal activity modulates cochlear responses in chinchillas. [PDF]

PLoS ONE, 2012
BACKGROUND: The auditory efferent system has unique neuroanatomical pathways that connect the cerebral cortex with sensory receptor cells. Pyramidal neurons located in layers V and VI of the primary auditory cortex constitute descending projections to ...
Alex León, Diego Elgueda, María A Silva, Carlos M Hamamé, Paul H Delano   +4 more
doaj   +1 more source

Cochlear Implantation Outcomes in Patients With OTOF Mutations

Frontiers in Neuroscience, 2020
Auditory neuropathy is a special type of hearing loss caused by dysfunction of the synapse of the inner hair cells, the auditory nerve, and/or the auditory nerve itself.
Dandan Zheng, Xiao Liu
doaj   +1 more source

Differential roles for EphA and EphB signaling in segregation and patterning of central vestibulocochlear nerve projections. [PDF]

PLoS ONE, 2013
Auditory and vestibular afferents enter the brainstem through the VIIIth cranial nerve and find targets in distinct brain regions. We previously reported that the axon guidance molecules EphA4 and EphB2 have largely complementary expression patterns in ...
Michelle R Allen-Sharpley, Michelle Tjia, Karina S Cramer   +2 more
doaj   +1 more source

Metabolic decline in an insect ear: correlative or causative for age-related auditory decline?

Frontiers in Cell and Developmental Biology, 2023
One leading hypothesis for why we lose our hearing as we age is a decrease in ear metabolism. However, direct measurements of metabolism across a lifespan in any auditory system are lacking.
Thomas T. Austin, Christian L. Thomas, Clifton Lewis, Alix Blockley, Ben Warren   +4 more
doaj   +1 more source