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Development of a non-human primate model for preclinical research of a novel auditory nerve implant [PDF]

open access: yesFrontiers in Neuroscience
The cochlear implant is a widely available hearing restoration technology that can provide speech understanding in quiet environments. This technology struggles however, in noisy settings or situations involving multiple speakers.
Inderbir Sondh   +8 more
doaj   +2 more sources

Development of a feline model for preclinical research of a new translabyrinthine auditory nerve implant [PDF]

open access: yesFrontiers in Neuroscience
Cochlear implants are among the most successful neural prosthetic devices to date but exhibit poor frequency selectivity and the inability to consistently activate apical (low frequency) spiral ganglion neurons. These issues can limit hearing performance
W. Mitchel Thomas   +12 more
doaj   +2 more sources

Pilot Chronic Evaluation of a Slanted Electrode Array as an Auditory Nerve Implant [PDF]

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Objective: The purpose of this paper is to present a chronic, preclinical, pilot study of a multi-electrode auditory nerve implant. To date, the most successful auditory neuroprosthesis is the cochlear implant, but these devices have known limitations ...
W. Mitchel Thomas   +9 more
doaj   +2 more sources

Clinical value of auditory nerve enhancement in idiopathic sudden sensorineural hearing loss: a retrospective study [PDF]

open access: yesFrontiers in Neurology
BackgroundThe pathogenesis of idiopathic sudden sensorineural hearing loss remains unclear, and no substantial breakthroughs have been achieved in its treatment.
Xiao Sun   +11 more
doaj   +2 more sources

The auditory nerve implant—concept and device description of a novel electrical auditory prosthesis [PDF]

open access: yesBioelectronic Medicine
The cochlear implant (CI) is considered one of the most successful neural prostheses, enabling deaf individuals to achieve intelligible speech perception.
Thomas Lenarz   +24 more
doaj   +2 more sources

Electrocochleography in Auditory Neuropathy Related to Mutations in the OTOF or OPA1 Gene

open access: yesAudiology Research, 2021
Auditory Neuropathy (AN) is characterized by disruption of temporal coding of acoustic signals in auditory nerve fibers resulting in alterations of auditory perceptions. Mutations in several genes have been associated to the most forms of AN.
Rosamaria Santarelli   +5 more
doaj   +1 more source

Intracochlear Auditory Nerve Monitoring and Cochlear Implantation After Total Resection of a Vestibular Schwannoma: Case Report

open access: yesB-ENT, 2023
The aim is to present a case of cochlear implantation (CI) after vestibular schwannoma (VS) resection and intracochlear auditory nerve moni toring. The case of a 53-year-old man with left-sided iatrogenic dehiscence of the posterior semicircular canal ...
Griet Mertens   +3 more
doaj   +3 more sources

Cervical and ocular vestibular evoked myogenic potentials test results in individuals with auditory neuropathy spectrum disorders

open access: yesAudiology Research, 2013
“Auditory neuropathy spectrum disorder” is a clinical disorder where the outer hair cell functioning is intact but the functioning of the auditory nerve is affected.
Sujeet Kumar Sinha   +2 more
doaj   +3 more sources

Auditory cortex basal activity modulates cochlear responses in chinchillas. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: The auditory efferent system has unique neuroanatomical pathways that connect the cerebral cortex with sensory receptor cells. Pyramidal neurons located in layers V and VI of the primary auditory cortex constitute descending projections to ...
Alex León   +4 more
doaj   +1 more source

Cochlear Implantation Outcomes in Patients With OTOF Mutations

open access: yesFrontiers in Neuroscience, 2020
Auditory neuropathy is a special type of hearing loss caused by dysfunction of the synapse of the inner hair cells, the auditory nerve, and/or the auditory nerve itself.
Dandan Zheng, Xiao Liu
doaj   +1 more source

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