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Contribution of auditory nerve fibers to compound action potential of the auditory nerve
Journal of Neurophysiology, 2014Sound-evoked compound action potential (CAP), which captures the synchronous activation of the auditory nerve fibers (ANFs), is commonly used to probe deafness in experimental and clinical settings. All ANFs are believed to contribute to CAP threshold and amplitude: low sound pressure levels activate the high-spontaneous rate (SR) fibers, and ...
Jérôme, Bourien +9 more
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Integrated Profile to Assess Auditory Nerve-Auditory Pathway Integrity
ORL, 2009<i>Purpose:</i> To evaluate the Integrated Cochlear Profile for Assessing Auditory Nerve-Auditory Pathway Integrity (ICP-API), as proposed by our group, in the selection of cochlear implant candidates. <i>Procedures:</i> The API of the candidates for cochlear implantation were assessed with the ICP-API, which consists of 5 ...
Wei-Jia, Kong +7 more
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2019
The transduction process in the cochlea requires patent hair cells. Population responses that reflect this patency are the cochlear microphonic (CM) and summating potential (SP). They can be measured using electrocochleography (ECochG). The CM reflects the sound waveform in the form of outer hair cell (OHC) depolarization and hyperpolarization, and the
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The transduction process in the cochlea requires patent hair cells. Population responses that reflect this patency are the cochlear microphonic (CM) and summating potential (SP). They can be measured using electrocochleography (ECochG). The CM reflects the sound waveform in the form of outer hair cell (OHC) depolarization and hyperpolarization, and the
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Experimental Grafting of the Auditory Nerve
Archives of Otolaryngology - Head and Neck Surgery, 1978The auditory nerve of five cats was sectioned unilaterally. Its proximal stump was immediately sutured to the proximal stump of the simultaneously severed facial nerve to study afferent sensory nerve regeneration. After time intervals of nine to 18 months, the nerve anastomosis was tested by electrical stimulation of the anastomosis and by recording ...
M E, Wigand +3 more
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Auditory Nerve: Electrical Stimulation in Man
Science, 1965Auditory perceptions produced in a person deaf to acoustic stimulation were studied by electrically exciting the auditory nerve through permanently implanted electrodes. Pulsed current as small as 1 microampere peak-to-peak could be perceived. Pitch, as reported by the subject, varied with electrode selection, current amplitude, and pulse repetition ...
F B, SIMMONS +6 more
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Analysis of the human auditory nerve
Hearing Research, 1989In human temporal bones of patients with normal hearing or sensory neural deafness, the cochlear neurons were quantitatively and qualitatively evaluated at the level of the osseous spiral lamina, the spiral ganglion and the cochlear nerve. We found from 32,000 to 31,000 myelinated nerve fibres in the cochlear nerve of normal hearing individuals and any
H, Spoendlin, A, Schrott
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Auditory nerve disease and auditory neuropathy spectrum disorders
Auris Nasus Larynx, 2016In 1996, a new type of bilateral hearing disorder was discerned and published almost simultaneously by Kaga et al. [1] and Starr et al. [2]. Although the pathophysiology of this disorder as reported by each author was essentially identical, Kaga used the term "auditory nerve disease" and Starr used the term "auditory neuropathy".
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Laser stimulation of the auditory nerve
Lasers in Surgery and Medicine, 2006AbstractBackground and ObjectivesFor centuries, electric current has been used to stimulate neurons. Shortcomings of electrical stimulation include the contact between the stimulating electrode and the tissue, and the non‐selective stimulation of the tissue.
Agnella D, Izzo +3 more
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Transplantation of conditionally immortal auditory neuroblasts to the auditory nerve
European Journal of Neuroscience, 2007AbstractCell transplantation is a realistic potential therapy for replacement of auditory sensory neurons and could benefit patients with cochlear implants or acoustic neuropathies. The procedure involves many experimental variables, including the nature and conditioning of donor cells, surgical technique and degree of degeneration in the host tissue ...
Sekiya, T +5 more
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Curious oddments of auditory-nerve studies
Hearing Research, 1990Three interesting theoretical issues are presented to illustrate how certain isolated observations on auditory-nerve activity can be puzzling until other, seemingly unrelated phenomena are documented. The issues are (1) disinhibition; (2) 'peak-splitting'; and (3) independence of spike generation in primary neurons innervating the same inner-hair cell.
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