The auxiliary subunit α2δ3 modulates the expression and function of voltage-gated calcium channels. Here we show that α2δ3 mRNA is expressed in spiral ganglion neurons and auditory brainstem nuclei and that the protein is required for normal acoustic ...
A. Pirone +12 more
semanticscholar +1 more source
Nanofibrous scaffolds for the guidance of stem cell-derived neurons for auditory nerve regeneration. [PDF]
Impairment of spiral ganglion neurons (SGNs) of the auditory nerve is a major cause for hearing loss occurring independently or in addition to sensory hair cell damage. Unfortunately, mammalian SGNs lack the potential for autonomous regeneration.
Sandra Hackelberg +12 more
doaj +1 more source
The connections of the inferior colliculus and the organization of the brainstem auditory system in the greater horseshoe bat (Rhinolophus ferrumequinum) [PDF]
The connections of the inferior colliculus, the mammalian midbrain auditory center, were determined in the greater horseshoe bat (Rhinolophus ferrumequinum), using the horseradish peroxidase method.
Adams +70 more
core +1 more source
Objectives. To study possible nerve regeneration of a damaged auditory nerve by the use of stem cell transplantation. Methods. We transplanted HNPCs to the rat AN trunk by the internal auditory meatus (IAM).
Y. Jiao +7 more
semanticscholar +1 more source
Age-Related Changes in Immune Cells of the Human Cochlea
Age-related hearing loss is a chronic degenerative disorder affecting one in two individuals above the age of 75. Current population projections predict a steady climb in the number of older individuals making the search for interventions to prevent or ...
Kenyaria V. Noble +5 more
doaj +1 more source
Variation and protection of the chorda tympani nerve in endoscopic ear surgery
Objective To observe and summarize variations of the chorda tympani nerve to effectively protect it during surgery. Methods Surgical videos of patients undergoing endoscopic ear surgery in the past 3 years were retrospectively observed to identify chorda
Li Quancheng, Zhong Jiangtao, Chai Liang
doaj +1 more source
NAVIS: Neuromorphic Auditory VISualizer Tool [PDF]
This software presents diverse utilities to perform the first post-processing layer taking the neuromorphic auditory sensors (NAS) information. The used NAS implements in FPGA a cascade filters architecture, imitating the behavior of the basilar membrane
Domínguez Morales, Juan Pedro +3 more
core
Intraoperative Neurophysiological Monitoring for Endoscopic Endonasal Approaches to the Skull Base: A Technical Guide. [PDF]
Intraoperative neurophysiological monitoring during endoscopic, endonasal approaches to the skull base is both feasible and safe. Numerous reports have recently emerged from the literature evaluating the efficacy of different neuromonitoring tests during
Doan, Adam T. +6 more
core +3 more sources
Loss of central auditory processing in a mouse model of Canavan disease.
Canavan Disease (CD) is a leukodystrophy caused by homozygous null mutations in the gene encoding aspartoacylase (ASPA). ASPA-deficiency is characterized by severe psychomotor retardation, and excessive levels of the ASPA substrate N-acetylaspartate (NAA)
Georg von Jonquieres +5 more
doaj +1 more source
Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]
This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
core +3 more sources

