Results 71 to 80 of about 58,385 (334)

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Intensity coding in the auditory nerve [PDF]

The Journal of the Acoustical Society of America, 1984
The mechanisms by which intensity is coded in the discharges of single auditory nerve fibers have not been fully determined, although hypotheses involving changes in discharge rate fiber recruitment have been proposed. In this paper, we will review the characteristics of auditory nerve fiber responses that may code for loudness growth and intensity ...
Edward J. Walsh, JoAnn McGee
openaire   +2 more sources

Neural Plasticity and Hearing‐Speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation

Advanced Science, EarlyView.
Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang, Yongchuan Chai, Yiwen Zhang, Huan Jia, Zhaoyan Wang, Zhihua Zhang, Zhili Wang, Jie Chen, Xue Wang, Yun Li, Ying Chen, Hao Wu   +11 more
wiley   +1 more source

Functional connectivity in behavioral variant frontotemporal dementia

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Decreased FC in the Salience Network (SN) is the most consistent finding in bvFTD. The brain's functional architecture is less interconnected and efficient in bvFTD. Symptom, behavior, cognition and disease severity are associated with changes in FC. Abstract Introduction Functional connectivity (FC)—which reflects relationships between neural activity
Luiz Kobuti Ferreira, Olof Lindberg, Alexander F Santillo, Lars‐Olof Wahlund   +3 more
wiley   +1 more source

Acoustic Noise of MRI Scans of the Internal Auditory Canal and Potential for Intracochlear Physiological Changes [PDF]

arXiv, 2012
Magnetic resonance imaging (MRI) is a widely used medical imaging technique to assess the health of the auditory (vestibulocochlear) nerve. A well known problem with MRI machines is that the acoustic noise they generate during a scan can cause auditory temporary threshold shifts (TTS) in humans.
arxiv  

Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional Gjb2 Null Mice Model

Advanced Science, EarlyView.
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang, Li Zhang, Sen Chen, Le Xie, Yue Qiu, Chenyang Kong, Ge Yin, Weijia Kong, Yu Sun   +8 more
wiley   +1 more source

Quantitative electroencephalographic analysis of delirium tremens development following alcohol‐withdrawal seizure based on a small number of male cases

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Considering the complications related to alcohol withdrawal syndrome (AWS) such as seizure, delirium tremens and cardiac arrhythmia, it is important to identify the risk of delirium tremens (DT) following AWS and enhance preventive strategies. We observed the characteristics of quantitative electroencephalography in patients with AWS, specifically who ...
Jee‐Eun Yoon, Heejung Mo, Dong Wook Kim, Hee‐Jin Im   +3 more
wiley   +1 more source

Intracochlear Auditory Nerve Monitoring and Cochlear Implantation After Total Resection of a Vestibular Schwannoma: Case Report

B-ENT
The aim is to present a case of cochlear implantation (CI) after vestibular schwannoma (VS) resection and intracochlear auditory nerve monitoring. The case of a 53-year-old man with left-sided iatrogenic dehiscence of the posterior semicircular canal ...
Griet Mertens, Marc Jan-Willem Lammers, Olivier Vanderveken, Vincent Van Rompaey   +3 more
doaj   +1 more source

METHOD OF AUDITORY EVOKED POTENTIALS IN THE SURGICAL TREATMENT OF CEREBELLOPONTINE ANGLE TUMORS

Vіsnik Naukovih Doslіdžen', 2017
This article presents a review of literature on cerebellopontine angle tumors, anatomy and physiology of the vestibular nerve, intraoperative neurophysiological monitoring and method of registration of auditory evoked potentials.
O. S. Herasymenko, V. I. Smolanka, A. V. Smolanka, O. S. Sechko   +3 more
doaj   +1 more source

Loss of β4-spectrin impairs Nav channel clustering at the heminode and temporal fidelity of presynaptic spikes in developing auditory brain

Scientific Reports, 2022
Beta-4 (β4)-spectrin, encoded by the gene Sptbn4, is a cytoskeleton protein found at nodes and the axon initial segments (AIS). Sptbn4 mutations are associated with myopathy, neuropathy, and auditory deficits in humans.
Kaila Nip, Sean Kashiwagura, Jun Hee Kim
doaj   +1 more source