Results 71 to 80 of about 602,896 (302)

Age-Related Changes in Immune Cells of the Human Cochlea

Frontiers in Neurology, 2019
Age-related hearing loss is a chronic degenerative disorder affecting one in two individuals above the age of 75. Current population projections predict a steady climb in the number of older individuals making the search for interventions to prevent or ...
Kenyaria V. Noble, Ting Liu, Lois J. Matthews, Bradley A. Schulte, Bradley A. Schulte, Hainan Lang   +5 more
doaj   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Binaural factors in auditory continuity

, 2002
Presented at the 8th International Conference on Auditory Display (ICAD), Kyoto, Japan, July 2-5, 2002.Presented at the 8th International Conference on Auditory Display (ICAD), Kyoto, Japan, July 2-5, 2002.Auditory continuity is a powerful illusion which
Darwin, C. J., Akeroyd, M. A., Hukin, R. W.   +2 more
core   +1 more source

Intracochlear Auditory Nerve Monitoring and Cochlear Implantation After Total Resection of a Vestibular Schwannoma: Case Report

B-ENT
The aim is to present a case of cochlear implantation (CI) after vestibular schwannoma (VS) resection and intracochlear auditory nerve monitoring. The case of a 53-year-old man with left-sided iatrogenic dehiscence of the posterior semicircular canal ...
Griet Mertens, Marc Jan-Willem Lammers, Olivier Vanderveken, Vincent Van Rompaey   +3 more
doaj   +1 more source

Wearable Electro‐Thermal Haptic Stimulator Driven by a Self‐Powered Tactile Sensor for Realistic Stimulus Replication

Advanced Science, EarlyView.
We present a stimulus‐replicating system combining a tactile sensor with a wearable Peltier thermotactile module and concentric electrotactile electrode. Signals encoding pressure and temperature drive the stimulators to reproduce mechano‐thermal cues on the skin. AlN/PDMS encapsulation and SA/LA PSA ensure mechanical compliance and thermal efficiency.
Ey‐In Lee, Chae‐Young Kang, Kyuhyun Hwang, Jongbaeg Kim, Jin‐Woo Park   +4 more
wiley   +1 more source

Loss of central auditory processing in a mouse model of Canavan disease.

PLoS ONE, 2014
Canavan Disease (CD) is a leukodystrophy caused by homozygous null mutations in the gene encoding aspartoacylase (ASPA). ASPA-deficiency is characterized by severe psychomotor retardation, and excessive levels of the ASPA substrate N-acetylaspartate (NAA)
Georg von Jonquieres, Kristina E Froud, Claudia B Klugmann, Ann C Y Wong, Gary D Housley, Matthias Klugmann   +5 more
doaj   +1 more source

Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing

Advanced Science, EarlyView.
A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang, Lei Zhao, Haoyuan Yao, Qiongshan Zhang, Fuzhen Xuan, Bin Zhang   +5 more
wiley   +1 more source

Hemifacial spasms caused by compression of the labyrinthine artery on the facial nerve in the internal auditory canal: a case report and review of the literature

Journal of Medical Case Reports
Purpose/Aim Hemifacial spasm caused by compression of the facial nerve in the internal auditory canal is very rare, as only 10 preoperative cases have been confirmed.
Zhifei Guo, Xiangyu Zhang, Bing Zhao
doaj   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source